› 5lsd

Solution NMR

recombinant mouse Nerve Growth Factor

Released:
DOI: 10.2210/pdb5lsd/pdb
PDB entry 5lsd coloured by chain, ensemble of 20 models, front view.
PDB entry 5lsd coloured by chain, ensemble of 20 models, side view.
PDB entry 5lsd coloured by chain, ensemble of 20 models, top view.
Source organism: Mus musculus
Primary publication:
Conformational Rigidity within Plasticity Promotes Differential Target Recognition of Nerve Growth Factor.
Paoletti F, de Chiara C, Kelly G, Covaceuszach S, Malerba F, Yan R, Lamba D, Cattaneo A, Pastore A
OpenAccess logo Front Mol Biosci 3 83 (2016)
PMID: 28083536

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-134072 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Beta-nerve growth factor Chains: A, B
Molecule details ›
Chains: A, B
Length: 118 amino acids
Theoretical weight: 13.28 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P01139 (Residues: 122-239; Coverage: 53%)
Gene names: Ngf, Ngfb
Sequence domains: Nerve growth factor family
Structure domains: Cystine-knot cytokines

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 86%
Refinement method: molecular dynamics
Expression system: Escherichia coli

Quick links

Citations

4 citation in other articles

On the mechanism of calcium-dependent activation of NADPH oxidase 5 (NOX5).
Millana Fañanás et al. (2020)
3 more

2 mentions without citation

Conformational Rigidity within Plasticity Promotes Differential Target Recognition of Nerve Growth Factor.
Paoletti et al. (2016)
1 more