Articles - 5lzx mentioned but not cited (2)
- Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes. Shao S, Murray J, Brown A, Taunton J, Ramakrishnan V, Hegde RS. Cell 167 1229-1240.e15 (2016)
- Functionally distinct roles for eEF2K in the control of ribosome availability and p-body abundance. Smith PR, Loerch S, Kunder N, Stanowick AD, Lou TF, Campbell ZT. Nat Commun 12 6789 (2021)
Reviews citing this publication (21)
- Roadblocks and resolutions in eukaryotic translation. Schuller AP, Green R. Nat Rev Mol Cell Biol 19 526-541 (2018)
- Translation Elongation and Recoding in Eukaryotes. Dever TE, Dinman JD, Green R. Cold Spring Harb Perspect Biol 10 a032649 (2018)
- Nonsense-Mediated mRNA Decay Begins Where Translation Ends. Karousis ED, Mühlemann O. Cold Spring Harb Perspect Biol 11 a032862 (2019)
- Translation Termination and Ribosome Recycling in Eukaryotes. Hellen CUT. Cold Spring Harb Perspect Biol 10 a032656 (2018)
- mRNA Translation Gone Awry: Translation Fidelity and Neurological Disease. Kapur M, Ackerman SL. Trends Genet 34 218-231 (2018)
- Translational recoding: canonical translation mechanisms reinterpreted. Rodnina MV, Korniy N, Klimova M, Karki P, Peng BZ, Senyushkina T, Belardinelli R, Maracci C, Wohlgemuth I, Samatova E, Peske F. Nucleic Acids Res 48 1056-1067 (2020)
- Transfer RNAs: diversity in form and function. Berg MD, Brandl CJ. RNA Biol 18 316-339 (2021)
- Ribosome-associated quality-control mechanisms from bacteria to humans. Filbeck S, Cerullo F, Pfeffer S, Joazeiro CAP. Mol Cell 82 1451-1466 (2022)
- Detecting and Rescuing Stalled Ribosomes. Yip MCJ, Shao S. Trends Biochem Sci 46 731-743 (2021)
- A Quick Guide to Small-Molecule Inhibitors of Eukaryotic Protein Synthesis. Dmitriev SE, Vladimirov DO, Lashkevich KA. Biochemistry (Mosc) 85 1389-1421 (2020)
- ABC-F translation factors: from antibiotic resistance to immune response. Fostier CR, Monlezun L, Ousalem F, Singh S, Hunt JF, Boël G. FEBS Lett 595 675-706 (2021)
- Extensions, Extra Factors, and Extreme Complexity: Ribosomal Structures Provide Insights into Eukaryotic Translation. Weisser M, Ban N. Cold Spring Harb Perspect Biol 11 a032367 (2019)
- Structural Heterogeneities of the Ribosome: New Frontiers and Opportunities for Cryo-EM. Poitevin F, Kushner A, Li X, Dao Duc K. Molecules 25 E4262 (2020)
- Features and factors that dictate if terminating ribosomes cause or counteract nonsense-mediated mRNA decay. Embree CM, Abu-Alhasan R, Singh G. J Biol Chem 298 102592 (2022)
- On the Need to Tell Apart Fraternal Twins eEF1A1 and eEF1A2, and Their Respective Outfits. Mills A, Gago F. Int J Mol Sci 22 6973 (2021)
- Structural snapshot of the cholesterol-transport ATP-binding cassette proteins 1. Xavier BM, Jennings WJ, Zein AA, Wang J, Lee JY. Biochem Cell Biol 97 224-233 (2019)
- The Structural Dynamics of Translation. Korostelev AA. Annu Rev Biochem 91 245-267 (2022)
- Molecular Insights into Determinants of Translational Readthrough and Implications for Nonsense Suppression Approaches. Lombardi S, Testa MF, Pinotti M, Branchini A. Int J Mol Sci 21 E9449 (2020)
- Diversity and Similarity of Termination and Ribosome Rescue in Bacterial, Mitochondrial, and Cytoplasmic Translation. Korostelev AA. Biochemistry (Mosc) 86 1107-1121 (2021)
- A ubiquitin language communicates ribosomal distress. Monem PC, Arribere JA. Semin Cell Dev Biol 154 131-137 (2024)
- Two "Edges" in Our Knowledge on the Functions of Ribosomal Proteins: The Revealed Contributions of Their Regions to Translation Mechanisms and the Issues of Their Extracellular Transport by Exosomes. Ochkasova A, Arbuzov G, Malygin A, Graifer D. Int J Mol Sci 24 11458 (2023)
Articles citing this publication (92)
- The human 18S rRNA m6A methyltransferase METTL5 is stabilized by TRMT112. van Tran N, Ernst FGM, Hawley BR, Zorbas C, Ulryck N, Hackert P, Bohnsack KE, Bohnsack MT, Jaffrey SR, Graille M, Lafontaine DLJ. Nucleic Acids Res 47 7719-7733 (2019)
- ZNF598 Is a Quality Control Sensor of Collided Ribosomes. Juszkiewicz S, Chandrasekaran V, Lin Z, Kraatz S, Ramakrishnan V, Hegde RS. Mol Cell 72 469-481.e7 (2018)
- High-Resolution Ribosome Profiling Defines Discrete Ribosome Elongation States and Translational Regulation during Cellular Stress. Wu CC, Zinshteyn B, Wehner KA, Green R. Mol Cell 73 959-970.e5 (2019)
- Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome. Bhatt PR, Scaiola A, Loughran G, Leibundgut M, Kratzel A, Meurs R, Dreos R, O'Connor KM, McMillan A, Bode JW, Thiel V, Gatfield D, Atkins JF, Ban N. Science 372 1306-1313 (2021)
- Variant ribosomal RNA alleles are conserved and exhibit tissue-specific expression. Parks MM, Kurylo CM, Dass RA, Bojmar L, Lyden D, Vincent CT, Blanchard SC. Sci Adv 4 eaao0665 (2018)
- Mechanism of ribosome stalling during translation of a poly(A) tail. Chandrasekaran V, Juszkiewicz S, Choi J, Puglisi JD, Brown A, Shao S, Ramakrishnan V, Hegde RS. Nat Struct Mol Biol 26 1132-1140 (2019)
- The ASC-1 Complex Disassembles Collided Ribosomes. Juszkiewicz S, Speldewinde SH, Wan L, Svejstrup JQ, Hegde RS. Mol Cell 79 603-614.e8 (2020)
- Ribosome collisions trigger cis-acting feedback inhibition of translation initiation. Juszkiewicz S, Slodkowicz G, Lin Z, Freire-Pritchett P, Peak-Chew SY, Hegde RS. Elife 9 e60038 (2020)
- A single H/ACA small nucleolar RNA mediates tumor suppression downstream of oncogenic RAS. McMahon M, Contreras A, Holm M, Uechi T, Forester CM, Pang X, Jackson C, Calvert ME, Chen B, Quigley DA, Luk JM, Kelley RK, Gordan JD, Gill RM, Blanchard SC, Ruggero D. Elife 8 e48847 (2019)
- RQT complex dissociates ribosomes collided on endogenous RQC substrate SDD1. Matsuo Y, Tesina P, Nakajima S, Mizuno M, Endo A, Buschauer R, Cheng J, Shounai O, Ikeuchi K, Saeki Y, Becker T, Beckmann R, Inada T. Nat Struct Mol Biol 27 323-332 (2020)
- Detailed Dissection and Critical Evaluation of the Pfizer/BioNTech and Moderna mRNA Vaccines. Xia X. Vaccines (Basel) 9 734 (2021)
- The dual methyltransferase METTL13 targets N terminus and Lys55 of eEF1A and modulates codon-specific translation rates. Jakobsson ME, Małecki JM, Halabelian L, Nilges BS, Pinto R, Kudithipudi S, Munk S, Davydova E, Zuhairi FR, Arrowsmith CH, Jeltsch A, Leidel SA, Olsen JV, Falnes PØ. Nat Commun 9 3411 (2018)
- Structures of translationally inactive mammalian ribosomes. Brown A, Baird MR, Yip MC, Murray J, Shao S. Elife 7 e40486 (2018)
- Eukaryotic translational termination efficiency is influenced by the 3' nucleotides within the ribosomal mRNA channel. Cridge AG, Crowe-McAuliffe C, Mathew SF, Tate WP. Nucleic Acids Res 46 1927-1944 (2018)
- Structural and Functional Insights into Human Re-initiation Complexes. Weisser M, Schäfer T, Leibundgut M, Böhringer D, Aylett CHS, Ban N. Mol Cell 67 447-456.e7 (2017)
- TTC5 mediates autoregulation of tubulin via mRNA degradation. Lin Z, Gasic I, Chandrasekaran V, Peters N, Shao S, Mitchison TJ, Hegde RS. Science 367 100-104 (2020)
- Identification of the amino acids inserted during suppression of CFTR nonsense mutations and determination of their functional consequences. Xue X, Mutyam V, Thakerar A, Mobley J, Bridges RJ, Rowe SM, Keeling KM, Bedwell DM. Hum Mol Genet 26 3116-3129 (2017)
- Translational termination without a stop codon. James NR, Brown A, Gordiyenko Y, Ramakrishnan V. Science 354 1437-1440 (2016)
- Tma64/eIF2D, Tma20/MCT-1, and Tma22/DENR Recycle Post-termination 40S Subunits In Vivo. Young DJ, Makeeva DS, Zhang F, Anisimova AS, Stolboushkina EA, Ghobakhlou F, Shatsky IN, Dmitriev SE, Hinnebusch AG, Guydosh NR. Mol Cell 71 761-774.e5 (2018)
- In vitro analysis of RQC activities provides insights into the mechanism and function of CAT tailing. Osuna BA, Howard CJ, Kc S, Frost A, Weinberg DE. Elife 6 e27949 (2017)
- Structure and function of yeast Lso2 and human CCDC124 bound to hibernating ribosomes. Wells JN, Buschauer R, Mackens-Kiani T, Best K, Kratzat H, Berninghausen O, Becker T, Gilbert W, Cheng J, Beckmann R. PLoS Biol 18 e3000780 (2020)
- Structural and mutational analysis of the ribosome-arresting human XBP1u. Shanmuganathan V, Schiller N, Magoulopoulou A, Cheng J, Braunger K, Cymer F, Berninghausen O, Beatrix B, Kohno K, von Heijne G, Beckmann R. Elife 8 e46267 (2019)
- Visualization of translation termination intermediates trapped by the Apidaecin 137 peptide during RF3-mediated recycling of RF1. Graf M, Huter P, Maracci C, Peterek M, Rodnina MV, Wilson DN. Nat Commun 9 3053 (2018)
- Eukaryotic Translation Elongation is Modulated by Single Natural Nucleotide Derivatives in the Coding Sequences of mRNAs. Hoernes TP, Heimdörfer D, Köstner D, Faserl K, Nußbaumer F, Plangger R, Kreutz C, Lindner H, Erlacher MD. Genes (Basel) 10 E84 (2019)
- Ribosome inhibition by C9ORF72-ALS/FTD-associated poly-PR and poly-GR proteins revealed by cryo-EM. Loveland AB, Svidritskiy E, Susorov D, Lee S, Park A, Zvornicanin S, Demo G, Gao FB, Korostelev AA. Nat Commun 13 2776 (2022)
- Visualization of translation and protein biogenesis at the ER membrane. Gemmer M, Chaillet ML, van Loenhout J, Cuevas Arenas R, Vismpas D, Gröllers-Mulderij M, Koh FA, Albanese P, Scheltema RA, Howes SC, Kotecha A, Fedry J, Förster F. Nature 614 160-167 (2023)
- Long non-coding subgenomic flavivirus RNAs have extended 3D structures and are flexible in solution. Zhang Y, Zhang Y, Liu ZY, Cheng ML, Ma J, Wang Y, Qin CF, Fang X. EMBO Rep 20 e47016 (2019)
- Mechanisms that ensure speed and fidelity in eukaryotic translation termination. Lawson MR, Lessen LN, Wang J, Prabhakar A, Corsepius NC, Green R, Puglisi JD. Science 373 876-882 (2021)
- Molecular analysis of the ribosome recycling factor ABCE1 bound to the 30S post-splitting complex. Nürenberg-Goloub E, Kratzat H, Heinemann H, Heuer A, Kötter P, Berninghausen O, Becker T, Tampé R, Beckmann R. EMBO J 39 e103788 (2020)
- Structure of the mammalian ribosome as it decodes the selenocysteine UGA codon. Hilal T, Killam BY, Grozdanović M, Dobosz-Bartoszek M, Loerke J, Bürger J, Mielke T, Copeland PR, Simonović M, Spahn CMT. Science 376 1338-1343 (2022)
- Ataluren binds to multiple protein synthesis apparatus sites and competitively inhibits release factor-dependent termination. Huang S, Bhattacharya A, Ghelfi MD, Li H, Fritsch C, Chenoweth DM, Goldman YE, Cooperman BS. Nat Commun 13 2413 (2022)
- Mechanism of premature translation termination on a sense codon. Svidritskiy E, Demo G, Korostelev AA. J Biol Chem 293 12472-12479 (2018)
- Unresolved stalled ribosome complexes restrict cell-cycle progression after genotoxic stress. Stoneley M, Harvey RF, Mulroney TE, Mordue R, Jukes-Jones R, Cain K, Lilley KS, Sawarkar R, Willis AE. Mol Cell 82 1557-1572.e7 (2022)
- ABCE1 Controls Ribosome Recycling by an Asymmetric Dynamic Conformational Equilibrium. Gouridis G, Hetzert B, Kiosze-Becker K, de Boer M, Heinemann H, Nürenberg-Goloub E, Cordes T, Tampé R. Cell Rep 28 723-734.e6 (2019)
- Structural basis for the transition from translation initiation to elongation by an 80S-eIF5B complex. Wang J, Wang J, Shin BS, Kim JR, Dever TE, Puglisi JD, Fernández IS. Nat Commun 11 5003 (2020)
- Structures of the eukaryotic ribosome and its translational states in situ. Hoffmann PC, Kreysing JP, Khusainov I, Tuijtel MW, Welsch S, Beck M. Nat Commun 13 7435 (2022)
- eIF5B and eIF1A reorient initiator tRNA to allow ribosomal subunit joining. Lapointe CP, Grosely R, Sokabe M, Alvarado C, Wang J, Montabana E, Villa N, Shin BS, Dever TE, Fraser CS, Fernández IS, Puglisi JD. Nature 607 185-190 (2022)
- Transcriptome-wide investigation of stop codon readthrough in Saccharomyces cerevisiae. Mangkalaphiban K, He F, Ganesan R, Wu C, Baker R, Jacobson A. PLoS Genet 17 e1009538 (2021)
- Ribosome stalling is a signal for metabolic regulation by the ribotoxic stress response. Snieckute G, Genzor AV, Vind AC, Ryder L, Stoneley M, Chamois S, Dreos R, Nordgaard C, Sass F, Blasius M, López AR, Brynjólfsdóttir SH, Andersen KL, Willis AE, Frankel LB, Poulsen SS, Gatfield D, Gerhart-Hines Z, Clemmensen C, Bekker-Jensen S. Cell Metab 34 2036-2046.e8 (2022)
- The Israeli acute paralysis virus IRES captures host ribosomes by mimicking a ribosomal state with hybrid tRNAs. Acosta-Reyes F, Neupane R, Frank J, Fernández IS. EMBO J 38 e102226 (2019)
- An E3 ligase network engages GCN1 to promote the degradation of translation factors on stalled ribosomes. Oltion K, Carelli JD, Yang T, See SK, Wang HY, Kampmann M, Taunton J. Cell 186 346-362.e17 (2023)
- Directed hydroxyl radical probing reveals Upf1 binding to the 80S ribosomal E site rRNA at the L1 stalk. Schuller AP, Zinshteyn B, Enam SU, Green R. Nucleic Acids Res 46 2060-2073 (2018)
- Long-range interdomain communications in eIF5B regulate GTP hydrolysis and translation initiation. Huang BY, Fernández IS. Proc Natl Acad Sci U S A 117 1429-1437 (2020)
- Mammalian Hbs1L deficiency causes congenital anomalies and developmental delay associated with Pelota depletion and 80S monosome accumulation. O'Connell AE, Gerashchenko MV, O'Donohue MF, Rosen SM, Huntzinger E, Gleeson D, Galli A, Ryder E, Cao S, Murphy Q, Kazerounian S, Morton SU, Schmitz-Abe K, Gladyshev VN, Gleizes PE, Séraphin B, Agrawal PB. PLoS Genet 15 e1007917 (2019)
- A Two-Headed Monster to Avert Disaster: HBS1/SKI7 Is Alternatively Spliced to Build Eukaryotic RNA Surveillance Complexes. Brunkard JO, Baker B. Front Plant Sci 9 1333 (2018)
- Protein glutaminylation is a yeast-specific posttranslational modification of elongation factor 1A. Jank T, Belyi Y, Wirth C, Rospert S, Hu Z, Dengjel J, Tzivelekidis T, Andersen GR, Hunte C, Schlosser A, Aktories K. J Biol Chem 292 16014-16023 (2017)
- Termi-Luc: a versatile assay to monitor full-protein release from ribosomes. Susorov D, Egri S, Korostelev AA. RNA 26 2044-2050 (2020)
- Virus-assisted directed evolution of enhanced suppressor tRNAs in mammalian cells. Jewel D, Kelemen RE, Huang RL, Zhu Z, Sundaresh B, Cao X, Malley K, Huang Z, Pasha M, Anthony J, van Opijnen T, Chatterjee A. Nat Methods 20 95-103 (2023)
- Blasticidin S inhibits mammalian translation and enhances production of protein encoded by nonsense mRNA. Powers KT, Stevenson-Jones F, Yadav SKN, Amthor B, Bufton JC, Borucu U, Shen D, Becker JP, Lavysh D, Hentze MW, Kulozik AE, Neu-Yilik G, Schaffitzel C. Nucleic Acids Res 49 7665-7679 (2021)
- Exploring the interactions of short RNAs with the human 40S ribosomal subunit near the mRNA entry site by EPR spectroscopy. Malygin AA, Krumkacheva OA, Graifer DM, Timofeev IO, Ochkasova AS, Meschaninova MI, Venyaminova AG, Fedin MV, Bowman M, Karpova GG, Bagryanskaya EG. Nucleic Acids Res 47 11850-11860 (2019)
- Nsp1 of SARS-CoV-2 stimulates host translation termination. Shuvalov A, Shuvalova E, Biziaev N, Sokolova E, Evmenov K, Pustogarov N, Arnautova A, Matrosova V, Egorova T, Alkalaeva E. RNA Biol 18 804-817 (2021)
- Selective destabilization of polypeptides synthesized from NMD-targeted transcripts. Chu V, Feng Q, Lim Y, Shao S. Mol Biol Cell 32 ar38 (2021)
- Structural diversity and phylogenetic distribution of valyl tRNA-like structures in viruses. Sherlock ME, Hartwick EW, MacFadden A, Kieft JS. RNA 27 27-39 (2021)
- mRNA decoding in human is kinetically and structurally distinct from bacteria. Holm M, Natchiar SK, Rundlet EJ, Myasnikov AG, Watson ZL, Altman RB, Wang HY, Taunton J, Blanchard SC. Nature 617 200-207 (2023)
- ArfB can displace mRNA to rescue stalled ribosomes. Carbone CE, Demo G, Madireddy R, Svidritskiy E, Korostelev AA. Nat Commun 11 5552 (2020)
- CTELS: A Cell-Free System for the Analysis of Translation Termination Rate. Lashkevich KA, Shlyk VI, Kushchenko AS, Gladyshev VN, Alkalaeva EZ, Dmitriev SE. Biomolecules 10 E911 (2020)
- Conserved heterodimeric GTPase Rbg1/Tma46 promotes efficient translation in eukaryotic cells. Zeng F, Li X, Pires-Alves M, Chen X, Hawk CW, Jin H. Cell Rep 37 109877 (2021)
- Didemnin B and ternatin-4 differentially inhibit conformational changes in eEF1A required for aminoacyl-tRNA accommodation into mammalian ribosomes. Juette MF, Carelli JD, Rundlet EJ, Brown A, Shao S, Ferguson A, Wasserman MR, Holm M, Taunton J, Blanchard SC. Elife 11 e81608 (2022)
- Structural rationale for the cross-resistance of tumor cells bearing the A399V variant of elongation factor eEF1A1 to the structurally unrelated didemnin B, ternatin, nannocystin A and ansatrienin B. Sánchez-Murcia PA, Cortés-Cabrera Á, Gago F. J Comput Aided Mol Des 31 915-928 (2017)
- Tissue-specific dynamic codon redefinition in Drosophila. Hudson AM, Szabo NL, Loughran G, Wills NM, Atkins JF, Cooley L. Proc Natl Acad Sci U S A 118 e2012793118 (2021)
- mRNA regions where 80S ribosomes pause during translation elongation in vivo interact with protein uS19, a component of the decoding site. Babaylova ES, Gopanenko AV, Bulygin KN, Tupikin AE, Kabilov MR, Malygin AA, Karpova GG. Nucleic Acids Res 48 912-923 (2020)
- Dynamic association of human Ebp1 with the ribosome. Bhaskar V, Desogus J, Graff-Meyer A, Schenk AD, Cavadini S, Chao JA. RNA 27 411-419 (2021)
- Epigenetic Control of Translation Checkpoint and Tumor Progression via RUVBL1-EEF1A1 Axis. Li M, Yang L, Chan AKN, Pokharel SP, Liu Q, Mattson N, Xu X, Chang WH, Miyashita K, Singh P, Zhang L, Li M, Wu J, Wang J, Chen B, Chan LN, Lee J, Zhang XH, Rosen ST, Müschen M, Qi J, Chen J, Hiom K, Bishop AJR, Chen CW. Adv Sci (Weinh) 10 e2206584 (2023)
- Synthesis and single-molecule imaging reveal stereospecific enhancement of binding kinetics by the antitumour eEF1A antagonist SR-A3. Wang HY, Yang H, Holm M, Tom H, Oltion K, Al-Khdhairawi AAQ, Weber JF, Blanchard SC, Ruggero D, Taunton J. Nat Chem 14 1443-1450 (2022)
- The mechanism of error induction by the antibiotic viomycin provides insight into the fidelity mechanism of translation. Holm M, Mandava CS, Ehrenberg M, Sanyal S. Elife 8 e46124 (2019)
- Translation inhibitory elements from Hoxa3 and Hoxa11 mRNAs use uORFs for translation inhibition. Alghoul F, Laure S, Eriani G, Martin F. Elife 10 e66369 (2021)
- Misdecoding of rare CGA codon by translation termination factors, eRF1/eRF3, suggests novel class of ribosome rescue pathway in S. cerevisiae. Wada M, Ito K. FEBS J 286 788-802 (2019)
- Nuclear and cytoplasmic RNA exosomes and PELOTA1 prevent miRNA-induced secondary siRNA production in Arabidopsis. Vigh ML, Bressendorff S, Thieffry A, Arribas-Hernández L, Brodersen P. Nucleic Acids Res 50 1396-1415 (2022)
- Origin of the omnipotence of eukaryotic release factor 1. Lind C, Oliveira A, Åqvist J. Nat Commun 8 1425 (2017)
- The revolution of personalized pharmacotherapies for cystic fibrosis: what does the future hold? Oliver KE, Carlon MS, Pedemonte N, Lopes-Pacheco M. Expert Opin Pharmacother 24 1545-1565 (2023)
- Nitric oxide-induced ribosome collision activates ribosomal surveillance mechanisms. Ryder L, Arendrup FS, Martínez JF, Snieckute G, Pecorari C, Shah RA, Lund AH, Blasius M, Bekker-Jensen S. Cell Death Dis 14 467 (2023)
- A noncanonical RNA-binding domain of the fragile X protein, FMRP, elicits translational repression independent of mRNA G-quadruplexes. Scarpitti MR, Warrick JE, Yoder EL, Kearse MG. J Biol Chem 298 102660 (2022)
- Coupled protein quality control during nonsense-mediated mRNA decay. Inglis AJ, Guna A, Gálvez-Merchán Á, Pal A, Esantsi TK, Keys HR, Frenkel EM, Oania R, Weissman JS, Voorhees RM. J Cell Sci 136 jcs261216 (2023)
- Cryo-EM reconstruction of the human 40S ribosomal subunit at 2.15 Å resolution. Pellegrino S, Dent KC, Spikes T, Warren AJ. Nucleic Acids Res 51 4043-4054 (2023)
- Discovery of C13-Aminobenzoyl Cycloheximide Derivatives that Potently Inhibit Translation Elongation. Koga Y, Hoang EM, Park Y, Keszei AFA, Murray J, Shao S, Liau BB. J Am Chem Soc 143 13473-13477 (2021)
- Geometric alignment of aminoacyl-tRNA relative to catalytic centers of the ribosome underpins accurate mRNA decoding. Girodat D, Wieden HJ, Blanchard SC, Sanbonmatsu KY. Nat Commun 14 5582 (2023)
- Inhibition of translation termination by small molecules targeting ribosomal release factors. Ge X, Oliveira A, Hjort K, Bergfors T, Gutiérrez-de-Terán H, Andersson DI, Sanyal S, Åqvist J. Sci Rep 9 15424 (2019)
- Silencing of the tRNA Modification Enzyme Cdkal1 Effects Functional Insulin Synthesis in NIT-1 Cells: tRNALys3 Lacking ms2- (ms2t6A37) is Unable to Establish Sufficient Anticodon:Codon Interactions to Decode the Wobble Codon AAG. Narendran A, Vangaveti S, Ranganathan SV, Eruysal E, Craft M, Alrifai O, Chua FY, Sarachan K, Litwa B, Ramachandran S, Agris PF. Front Mol Biosci 7 584228 (2020)
- A Legionella toxin exhibits tRNA mimicry and glycosyl transferase activity to target the translation machinery and trigger a ribotoxic stress response. Subramanian A, Wang L, Moss T, Voorhies M, Sangwan S, Stevenson E, Pulido EH, Kwok S, Chalkley RJ, Li KH, Krogan NJ, Swaney DL, Burlingame AL, Floor SN, Sil A, Walter P, Mukherjee S. Nat Cell Biol 25 1600-1615 (2023)
- A Zpr1 co-chaperone mediates folding of eukaryotic translation elongation factor 1A via a GTPase cycle. McQuown AJ, Nelliat AR, Reif D, Sabbarini IM, Membreno BS, Wu CC, Denic V. Mol Cell 83 3108-3122.e13 (2023)
- Extended stop codon context predicts nonsense codon readthrough efficiency in human cells. Mangkalaphiban K, Fu L, Du M, Thrasher K, Keeling KM, Bedwell DM, Jacobson A. Nat Commun 15 2486 (2024)
- Visualization of translation reorganization upon persistent ribosome collision stress in mammalian cells. Fedry J, Silva J, Vanevic M, Fronik S, Mechulam Y, Schmitt E, des Georges A, Faller WJ, Förster F. Mol Cell 84 1078-1089.e4 (2024)
- A highly optimized human in vitro translation system. Bothe A, Ban N. Cell Rep Methods 4 100755 (2024)
- Boric acid intercepts 80S ribosome migration from AUG-stop by stabilizing eRF1. Tanaka M, Yokoyama T, Saito H, Nishimoto M, Tsuda K, Sotta N, Shigematsu H, Shirouzu M, Iwasaki S, Ito T, Fujiwara T. Nat Chem Biol 20 605-614 (2024)
- CLIP-Seq analysis enables the design of protective ribosomal RNA bait oligonucleotides against C9ORF72 ALS/FTD poly-GR pathophysiology. Ortega JA, Sasselli IR, Boccitto M, Fleming AC, Fortuna TR, Li Y, Sato K, Clemons TD, Mckenna ED, Nguyen TP, Anderson EN, Asin J, Ichida JK, Pandey UB, Wolin SL, Stupp SI, Kiskinis E. Sci Adv 9 eadf7997 (2023)
- Elongation factor 1A1 regulates metabolic substrate preference in mammalian cells. Wilson RB, Kozlov AM, Hatam Tehrani H, Twumasi-Ankrah JS, Chen YJ, Borrelli MJ, Sawyez CG, Maini S, Shepherd TG, Cumming RC, Betts DH, Borradaile NM. J Biol Chem 300 105684 (2024)
- KAT8-catalyzed lactylation promotes eEF1A2-mediated protein synthesis and colorectal carcinogenesis. Xie B, Zhang M, Li J, Cui J, Zhang P, Liu F, Wu Y, Deng W, Ma J, Li X, Pan B, Zhang B, Zhang H, Luo A, Xu Y, Li M, Pu Y. Proc Natl Acad Sci U S A 121 e2314128121 (2024)
- Methylation of elongation factor 1A by yeast Efm4 or human eEF1A-KMT2 involves a beta-hairpin recognition motif and crosstalks with phosphorylation. Hamey JJ, Nguyen A, Haddad M, Vázquez-Campos X, Pfeiffer PG, Wilkins MR. J Biol Chem 300 105639 (2024)
- The eRF1 degrader SRI-41315 acts as a molecular glue at the ribosomal decoding center. Coelho JPL, Yip MCJ, Oltion K, Taunton J, Shao S. Nat Chem Biol (2024)
- The flexible N-terminal motif of uL11 unique to eukaryotic ribosomes interacts with P-complex and facilitates protein translation. Yang L, Lee KM, Yu CW, Imai H, Choi AK, Banfield DK, Ito K, Uchiumi T, Wong KB. Nucleic Acids Res 50 5335-5348 (2022)
- Two alternative conformations of mRNA in the human ribosome during elongation and termination of translation as revealed by EPR spectroscopy. Bulygin KN, Timofeev IO, Malygin AA, Graifer DM, Meschaninova MI, Venyaminova AG, Krumkacheva OA, Fedin MV, Yu Frolova L, Karpova GG, Bagryanskaya EG. Comput Struct Biotechnol J 19 4702-4710 (2021)
- dCas13-mediated translational repression for accurate gene silencing in mammalian cells. Apostolopoulos A, Kawamoto N, Chow SYA, Tsuiji H, Ikeuchi Y, Shichino Y, Iwasaki S. Nat Commun 15 2205 (2024)