Function and Biology

S-adenosyl-L-homocysteine hydrolase from Bradyrhizobium elkanii in complex with adenosine and cordycepin

Source organism: Bradyrhizobium elkanii
Biochemical function: hydrolase activity
Biological process: L-homocysteine biosynthetic process
Cellular component: cytosol

Sequence families

Pfam Protein families (Pfam)
PF00670
Domain description: S-adenosyl-L-homocysteine hydrolase, NAD binding domain
Occurring in:
  1. Adenosylhomocysteinase
The deposited structure of PDB entry 5m5k contains 4 copies of Pfam domain PF00670 (S-adenosyl-L-homocysteine hydrolase, NAD binding domain) in Adenosylhomocysteinase. Showing 1 copy in chain C.

PF05221
Domain description: S-adenosyl-L-homocysteine hydrolase
Occurring in:
  1. Adenosylhomocysteinase
The deposited structure of PDB entry 5m5k contains 4 copies of Pfam domain PF05221 (S-adenosyl-L-homocysteine hydrolase) in Adenosylhomocysteinase. Showing 1 copy in chain C.

InterPro InterPro annotations
IPR000043
Domain description: Adenosylhomocysteinase-like
Occurring in:
  1. Adenosylhomocysteinase
IPR015878
Domain description: S-adenosyl-L-homocysteine hydrolase, NAD binding domain
Occurring in:
  1. Adenosylhomocysteinase
IPR020082
Domain description: S-adenosyl-L-homocysteine hydrolase, conserved site
Occurring in:
  1. Adenosylhomocysteinase
IPR036291
Domain description: NAD(P)-binding domain superfamily
Occurring in:
  1. Adenosylhomocysteinase
IPR042172
Domain description: Adenosylhomocysteinase-like superfamily
Occurring in:
  1. Adenosylhomocysteinase

Structure domains

CATH CATH domains
3.40.50.1480
Class: Alpha Beta
Architecture: 3-Layer(aba) Sandwich
Topology: Rossmann fold
Homology: Adenosylhomocysteinase-like
Occurring in:
  1. Adenosylhomocysteinase
The deposited structure of PDB entry 5m5k contains 4 copies of CATH domain 3.40.50.1480 (Rossmann fold) in Adenosylhomocysteinase. Showing 1 copy in chain C.
3.40.50.720
Class: Alpha Beta
Architecture: 3-Layer(aba) Sandwich
Topology: Rossmann fold
Homology: NAD(P)-binding Rossmann-like Domain
Occurring in:
  1. Adenosylhomocysteinase
The deposited structure of PDB entry 5m5k contains 4 copies of CATH domain 3.40.50.720 (Rossmann fold) in Adenosylhomocysteinase. Showing 1 copy in chain C.