› 5m6s

Electron Microscopy
4.8Å resolution

folding intermediate of spectrin R16

Released:
DOI: 10.2210/pdb5m6s/pdb
PDB entry 5m6s coloured by chain, front view.
PDB entry 5m6s coloured by chain, side view.
PDB entry 5m6s coloured by chain, top view.
Source organisms:
Primary publication:
Cotranslational folding of spectrin domains via partially structured states.
Nilsson OB, Nickson AA, Hollins JJ, Wickles S, Steward A, Beckmann R, von Heijne G, Clarke J
Nat Struct Mol Biol 24 221-225 (2017)
PMID: 28112730
Related structures: EMD-3451

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-139740 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Spectrin alpha chain, non-erythrocytic 1; Tryptophanase operon leader peptide Chain: A
Molecule details ›
Chain: A
Length: 169 amino acids
Theoretical weight: 19.37 KDa
Source organisms: Expression system: Escherichia coli
UniProt:
  • Canonical: P07751 (Residues: 1763-1872; Coverage: 4%)
  • Canonical: P0AD89 (Residues: 2-24; Coverage: 96%)
Gene names: JW3685, SPTA2, SPTAN1, b3707, tnaC, tnaL
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 4.8Å
Relevant EMDB volumes: EMD-3451
Expression system: Escherichia coli

Quick links

Citations

9 review citations

Nature and Regulation of Protein Folding on the Ribosome.
Waudby et al. (2019)
8 more