EC 2.5.1.61: Hydroxymethylbilane synthase
Reaction catalysed:
4 porphobilinogen + H(2)O = hydroxymethylbilane + 4 NH(3)
Systematic name:
Porphobilinogen:(4-(2-carboxyethyl)-3-(carboxymethyl)pyrrol-2-yl)methyltransferase (hydrolyzing)
Alternative Name(s):
- (4-(2-carboxyethyl)-3-(carboxymethyl)pyrrol-2-yl)methyltransferase (hydrolyzing)
- HMB-synthase
- Porphobilinogen ammonia-lyase (polymerizing)
- Porphobilinogen deaminase
- Pre-uroporphyrinogen synthase
- Uroporphyrinogen I synthase
- Uroporphyrinogen I synthetase
- Uroporphyrinogen synthase
- Uroporphyrinogen synthetase
GO terms
Biochemical function:
Biological process:
Cellular component:
Sequence families
Protein families (Pfam)
InterPro annotations
Structure domains
CATH domains
3.40.190.10
Class:
Alpha Beta
Architecture:
3-Layer(aba) Sandwich
Topology:
D-Maltodextrin-Binding Protein; domain 2
Homology:
Periplasmic binding protein-like II
Occurring in: