› 5msk

X-ray diffraction
3.6Å resolution

Mouse PA28beta

Released:
DOI: 10.2210/pdb5msk/pdb
Model geometry
Fit model/data
PDB entry 5msk coloured by chain, front view.
PDB entry 5msk coloured by chain, side view.
PDB entry 5msk coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
The Mammalian Proteasome Activator PA28 Forms an Asymmetric α4β3 Complex.
Huber EM, Groll M
Structure 25 1473-1480.e3 (2017)
PMID: 28867616

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo heptamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-161298 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Proteasome activator complex subunit 2 Chains: A, B, C, D, E, F, G
Molecule details ›
Chains: A, B, C, D, E, F, G
Length: 239 amino acids
Theoretical weight: 27.09 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P97372 (Residues: 1-239; Coverage: 100%)
Gene names: Pa28b1, Psme2
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: SLS BEAMLINE X06SA
Spacegroup: P21
Unit cell:
a: 86.84Å b: 132.61Å c: 90.93Å
α: 90° β: 92.19° γ: 90°
R-values:
R R work R free
0.243 0.242 0.263
Expression system: Escherichia coli BL21

Quick links

Citations

11 review citations

Regulation of proteasome assembly and activity in health and disease.
Rousseau et al. (2018)
10 more

2 mentions without citation

Functional Differences between Proteasome Subtypes.
Abi Habib et al. (2022)
1 more