Function and Biology Details
Reactions catalysed:
Autocatalytically cleaves itself from the polyprotein of the foot-and-mouth disease virus by hydrolysis of a Lys-|-Gly bond, but then cleaves host cell initiation factor eIF-4G at bonds -Gly-|-Arg- and -Lys-|-Arg-.
NTP + H(2)O = NDP + phosphate
Biochemical function:
Biological process:
- not assigned
Cellular component:
Structure analysis Details
Assembly composition:
hetero 240-mer (preferred)
Assembly name:
O1 Manisa VP1 and VP4 (preferred)
PDBe Complex ID:
PDB-CPX-112304 (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (4 distinct):