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D10N variant of beta-phosphoglucomutase from Lactococcus lactis trapped with native beta-glucose 1,6-bisphosphate intermediate to 1.9A resolution.

Source organism: Lactococcus lactis
Biochemical function: metal ion binding
Biological process: carbohydrate metabolic process
Cellular component: cytoplasm

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EC 5.4.2.6: Beta-phosphoglucomutase

Reaction catalysed:
Beta-D-glucose 1-phosphate = beta-D-glucose 6-phosphate
Systematic name:
Beta-D-glucose 1,6-phosphomutase
Alternative Name(s):
  • Beta-pgm (gene name)

GO terms

Sequence family

Pfam Protein family (Pfam)
PF00702
Domain description: haloacid dehalogenase-like hydrolase
Occurring in:
  1. Beta-phosphoglucomutase
The deposited structure of PDB entry 5ok1 contains 1 copy of Pfam domain PF00702 (haloacid dehalogenase-like hydrolase) in Beta-phosphoglucomutase. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR006439
Domain description: HAD hydrolase, subfamily IA
Occurring in:
  1. Beta-phosphoglucomutase
IPR010972
Domain description: Beta-phosphoglucomutase
Occurring in:
  1. Beta-phosphoglucomutase
IPR023198
Domain description: Phosphoglycolate phosphatase-like, domain 2
Occurring in:
  1. Beta-phosphoglucomutase
IPR041492
Domain description: Haloacid dehalogenase-like hydrolase
Occurring in:
  1. Beta-phosphoglucomutase
IPR023214
Domain description: HAD superfamily
Occurring in:
  1. Beta-phosphoglucomutase
IPR010976
Domain description: Beta-phosphoglucomutase hydrolase
Occurring in:
  1. Beta-phosphoglucomutase
IPR036412
Domain description: HAD-like superfamily
Occurring in:
  1. Beta-phosphoglucomutase

Structure domains

CATH CATH domains
3.40.50.1000
Class: Alpha Beta
Architecture: 3-Layer(aba) Sandwich
Topology: Rossmann fold
Homology: HAD superfamily/HAD-like
Occurring in:
  1. Beta-phosphoglucomutase
The deposited structure of PDB entry 5ok1 contains 1 copy of CATH domain 3.40.50.1000 (Rossmann fold) in Beta-phosphoglucomutase. Showing 1 copy in chain A.
1.10.150.240
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: DNA polymerase; domain 1
Homology: Putative phosphatase; domain 2
Occurring in:
  1. Beta-phosphoglucomutase
The deposited structure of PDB entry 5ok1 contains 1 copy of CATH domain 1.10.150.240 (DNA polymerase; domain 1) in Beta-phosphoglucomutase. Showing 1 copy in chain A.

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