EC 3.5.2.6: Beta-lactamase
Reaction catalysed:
A beta-lactam + H(2)O = a substituted beta-amino acid
Systematic name:
Beta-lactam hydrolase
Alternative Name(s):
- Ampicillinase
- Beta-lactamase A, B, C
- Beta-lactamase AME I
- Beta-lactamase I-III
- Cephalosporin-beta-lactamase
- Cephalosporinase
- Exopenicillinase
- Neutrapen
- Penicillin amido-beta-lactamhydrolase
- Penicillin beta-lactamase
- Penicillinase
- Penicillinase I, II
GO terms
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Sequence family
Structure domains
CATH domains
3.60.15.10
Class:
Alpha Beta
Architecture:
4-Layer Sandwich
Topology:
Metallo-beta-lactamase; Chain A
Homology:
Ribonuclease Z/Hydroxyacylglutathione hydrolase-like
Occurring in:
![The deposited structure of PDB entry <span class='highlight'>5q1z</span> contains 1 copy of CATH domain <span class='highlight'>3.60.15.10 (Metallo-beta-lactamase; Chain A)</span> in <span class='highlight'>DNA cross-link repair 1A protein</span>. Showing 1 copy in chain <span class='highlight'>A</span>. The deposited structure of PDB entry 5q1z contains 1 copy of CATH domain 3.60.15.10 (Metallo-beta-lactamase; Chain A) in DNA cross-link repair 1A protein. Showing 1 copy in chain A.](https://www.ebi.ac.uk/pdbe/static/entry/5q1z_1_A_CATH_3.60.15.10_image-200x200.png)