› 5qh9

X-ray diffraction
1.72Å resolution

PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of NUDT7 in complex with PCM-0102716

Released:
DOI: 10.2210/pdb5qh9/pdb
PDB entry 5qh9 coloured by chain, front view.
PDB entry 5qh9 coloured by chain, side view.
PDB entry 5qh9 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Krojer T, Talon R, Fairhead M, Diaz Saez L, Bradley AR, Aimon A, Collins P, Brandao-Neto J, Douangamath A, Ruda GF, Szommer T, Srikannathasan V, Elkins J, Spencer J, London N, Nelson A, Brennan PE, Huber K, Bountra C, Arrowsmith CH, Edwards A, von Delft F

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-533344 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Peroxisomal coenzyme A diphosphatase NUDT7 Chain: A
Molecule details ›
Chain: A
Length: 196 amino acids
Theoretical weight: 22.2 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P0C024 (Residues: 14-209; Coverage: 82%)
Gene name: NUDT7
Sequence domains: NUDIX domain

Ligands and Environments

2 bound ligands:
Ligand ACT 2 x ACT
Ligand GZY 1 x GZY
2 modified residues:
Ligand HYP 1 x HYP
Ligand CSO 1 x CSO

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04-1
Spacegroup: P321
Unit cell:
a: 124.671Å b: 124.671Å c: 41.174Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.185 0.184 0.206
Expression system: Escherichia coli

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