› 5sbz

X-ray diffraction
1.17Å resolution

CD44 PanDDA analysis group deposition -- The hyaluronan-binding domain of CD44 in complex with Z768399682

Released:
DOI: 10.2210/pdb5sbz/pdb
PDB entry 5sbz coloured by chain, front view.
PDB entry 5sbz coloured by chain, side view.
PDB entry 5sbz coloured by chain, top view.
Source organism: Mus musculus
Entry authors: Bradshaw WJ, Katis VL, Bezerra GA, Koekemoer L, von Delft F, Bountra C, Brennan PE, Gileadi O

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-147332 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
CD44 antigen Chain: A
Molecule details ›
Chain: A
Length: 152 amino acids
Theoretical weight: 16.97 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P15379 (Residues: 23-172; Coverage: 20%)
Gene names: Cd44, Ly-24
Sequence domains: Extracellular link domain

Ligands and Environments

3 bound ligands:
Ligand K0D 1 x K0D
Ligand DMS 3 x DMS
Ligand EDO 1 x EDO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04-1
Spacegroup: P21
Unit cell:
a: 30.942Å b: 82.239Å c: 32.234Å
α: 90° β: 117.9° γ: 90°
R-values:
R R work R free
0.145 0.144 0.166
Expression system: Escherichia coli

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