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5se8 Overview
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>5se8</span> coloured by chain, front view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>4 copies of <span class='highlight'>cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A</span>;</li> <li class='image_legend_li'>4 copies of <span class='highlight'>ZINC ION</span>;</li> <li class='image_legend_li'>4 copies of <span class='highlight'>MAGNESIUM ION</span>;</li> <li class='image_legend_li'>4 copies of <span class='highlight'>4-(azetidine-1-carbonyl)-2-methyl-N-[2-(1-methyl-3-phenyl-1H-1,2,4-triazol-5-yl)ethyl]-2,5-dihydro-1H-pyrazole-3-carboxamide</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/5se8_deposited_chain_front_image-800x800.png "PDB entry 5se8 coloured by chain, front view.")
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>5se8</span> coloured by chain, side view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>4 copies of <span class='highlight'>cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A</span>;</li> <li class='image_legend_li'>4 copies of <span class='highlight'>ZINC ION</span>;</li> <li class='image_legend_li'>4 copies of <span class='highlight'>MAGNESIUM ION</span>;</li> <li class='image_legend_li'>4 copies of <span class='highlight'>4-(azetidine-1-carbonyl)-2-methyl-N-[2-(1-methyl-3-phenyl-1H-1,2,4-triazol-5-yl)ethyl]-2,5-dihydro-1H-pyrazole-3-carboxamide</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/5se8_deposited_chain_side_image-800x800.png "PDB entry 5se8 coloured by chain, side view.")
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>5se8</span> coloured by chain, top view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>4 copies of <span class='highlight'>cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A</span>;</li> <li class='image_legend_li'>4 copies of <span class='highlight'>ZINC ION</span>;</li> <li class='image_legend_li'>4 copies of <span class='highlight'>MAGNESIUM ION</span>;</li> <li class='image_legend_li'>4 copies of <span class='highlight'>4-(azetidine-1-carbonyl)-2-methyl-N-[2-(1-methyl-3-phenyl-1H-1,2,4-triazol-5-yl)ethyl]-2,5-dihydro-1H-pyrazole-3-carboxamide</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/5se8_deposited_chain_top_image-800x800.png "PDB entry 5se8 coloured by chain, top view.")
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>5se8</span> coloured by chemically distinct molecules, front view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>4 copies of <span class='highlight'>cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A</span>;</li> <li class='image_legend_li'>4 copies of <span class='highlight'>ZINC ION</span>;</li> <li class='image_legend_li'>4 copies of <span class='highlight'>MAGNESIUM ION</span>;</li> <li class='image_legend_li'>4 copies of <span class='highlight'>4-(azetidine-1-carbonyl)-2-methyl-N-[2-(1-methyl-3-phenyl-1H-1,2,4-triazol-5-yl)ethyl]-2,5-dihydro-1H-pyrazole-3-carboxamide</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/5se8_deposited_chemically_distinct_molecules_front_image-800x800.png "PDB entry 5se8 coloured by chemically distinct molecules, front view.")
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>5se8</span> coloured by chemically distinct molecules, side view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>4 copies of <span class='highlight'>cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A</span>;</li> <li class='image_legend_li'>4 copies of <span class='highlight'>ZINC ION</span>;</li> <li class='image_legend_li'>4 copies of <span class='highlight'>MAGNESIUM ION</span>;</li> <li class='image_legend_li'>4 copies of <span class='highlight'>4-(azetidine-1-carbonyl)-2-methyl-N-[2-(1-methyl-3-phenyl-1H-1,2,4-triazol-5-yl)ethyl]-2,5-dihydro-1H-pyrazole-3-carboxamide</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/5se8_deposited_chemically_distinct_molecules_side_image-800x800.png "PDB entry 5se8 coloured by chemically distinct molecules, side view.")
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>5se8</span> coloured by chemically distinct molecules, top view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>4 copies of <span class='highlight'>cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A</span>;</li> <li class='image_legend_li'>4 copies of <span class='highlight'>ZINC ION</span>;</li> <li class='image_legend_li'>4 copies of <span class='highlight'>MAGNESIUM ION</span>;</li> <li class='image_legend_li'>4 copies of <span class='highlight'>4-(azetidine-1-carbonyl)-2-methyl-N-[2-(1-methyl-3-phenyl-1H-1,2,4-triazol-5-yl)ethyl]-2,5-dihydro-1H-pyrazole-3-carboxamide</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/5se8_deposited_chemically_distinct_molecules_top_image-800x800.png "PDB entry 5se8 coloured by chemically distinct molecules, top view.")
![<div class='caption-body'>Monomeric assembly 1 of PDB entry <span class='highlight'>5se8</span> contains 1 copy of <span class='highlight'>4-(azetidine-1-carbonyl)-2-methyl-N-[2-(1-methyl-3-phenyl-1H-1,2,4-triazol-5-yl)ethyl]-2,5-dihydro-1H-pyrazole-3-carboxamide</span>. Front view.</div>](https://www.ebi.ac.uk/pdbe/static/entry/5se8_entity_4_front_image-800x800.png "4-(azetidine-1-carbonyl)-2-methyl-N-[2-(1-methyl-3-phenyl-1H-1,2,4-triazol-5-yl)ethyl]-2,5-dihydro-1H-pyrazole-3-carboxamide in PDB entry 5se8, assembly 1, front view.")
![<div class='caption-body'>Monomeric assembly 1 of PDB entry <span class='highlight'>5se8</span> coloured by chemically distinct molecules, front view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>ZINC ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>MAGNESIUM ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>4-(azetidine-1-carbonyl)-2-methyl-N-[2-(1-methyl-3-phenyl-1H-1,2,4-triazol-5-yl)ethyl]-2,5-dihydro-1H-pyrazole-3-carboxamide</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/5se8_assembly_1_chemically_distinct_molecules_front_image-800x800.png "Monomeric assembly 1 of PDB entry 5se8 coloured by chemically distinct molecules, front view.")
![<div class='caption-body'>Monomeric assembly 1 of PDB entry <span class='highlight'>5se8</span> coloured by chemically distinct molecules, side view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>ZINC ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>MAGNESIUM ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>4-(azetidine-1-carbonyl)-2-methyl-N-[2-(1-methyl-3-phenyl-1H-1,2,4-triazol-5-yl)ethyl]-2,5-dihydro-1H-pyrazole-3-carboxamide</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/5se8_assembly_1_chemically_distinct_molecules_side_image-800x800.png "Monomeric assembly 1 of PDB entry 5se8 coloured by chemically distinct molecules, side view.")
![<div class='caption-body'>Monomeric assembly 1 of PDB entry <span class='highlight'>5se8</span> coloured by chemically distinct molecules, top view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>ZINC ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>MAGNESIUM ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>4-(azetidine-1-carbonyl)-2-methyl-N-[2-(1-methyl-3-phenyl-1H-1,2,4-triazol-5-yl)ethyl]-2,5-dihydro-1H-pyrazole-3-carboxamide</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/5se8_assembly_1_chemically_distinct_molecules_top_image-800x800.png "Monomeric assembly 1 of PDB entry 5se8 coloured by chemically distinct molecules, top view.")