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5sev Overview
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>5sev</span> coloured by chain, front view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>4 copies of <span class='highlight'>cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A</span>;</li> <li class='image_legend_li'>4 copies of <span class='highlight'>ZINC ION</span>;</li> <li class='image_legend_li'>4 copies of <span class='highlight'>MAGNESIUM ION</span>;</li> <li class='image_legend_li'>4 copies of <span class='highlight'>2,3,5-trimethyl-6-{2-[(4S)-1-methyl-4-phenyl-4,5-dihydro-1H-imidazol-2-yl]ethyl}pyrazine</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/5sev_deposited_chain_front_image-800x800.png "PDB entry 5sev coloured by chain, front view.")
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>5sev</span> coloured by chain, side view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>4 copies of <span class='highlight'>cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A</span>;</li> <li class='image_legend_li'>4 copies of <span class='highlight'>ZINC ION</span>;</li> <li class='image_legend_li'>4 copies of <span class='highlight'>MAGNESIUM ION</span>;</li> <li class='image_legend_li'>4 copies of <span class='highlight'>2,3,5-trimethyl-6-{2-[(4S)-1-methyl-4-phenyl-4,5-dihydro-1H-imidazol-2-yl]ethyl}pyrazine</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/5sev_deposited_chain_side_image-800x800.png "PDB entry 5sev coloured by chain, side view.")
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>5sev</span> coloured by chain, top view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>4 copies of <span class='highlight'>cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A</span>;</li> <li class='image_legend_li'>4 copies of <span class='highlight'>ZINC ION</span>;</li> <li class='image_legend_li'>4 copies of <span class='highlight'>MAGNESIUM ION</span>;</li> <li class='image_legend_li'>4 copies of <span class='highlight'>2,3,5-trimethyl-6-{2-[(4S)-1-methyl-4-phenyl-4,5-dihydro-1H-imidazol-2-yl]ethyl}pyrazine</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/5sev_deposited_chain_top_image-800x800.png "PDB entry 5sev coloured by chain, top view.")
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>5sev</span> coloured by chemically distinct molecules, front view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>4 copies of <span class='highlight'>cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A</span>;</li> <li class='image_legend_li'>4 copies of <span class='highlight'>ZINC ION</span>;</li> <li class='image_legend_li'>4 copies of <span class='highlight'>MAGNESIUM ION</span>;</li> <li class='image_legend_li'>4 copies of <span class='highlight'>2,3,5-trimethyl-6-{2-[(4S)-1-methyl-4-phenyl-4,5-dihydro-1H-imidazol-2-yl]ethyl}pyrazine</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/5sev_deposited_chemically_distinct_molecules_front_image-800x800.png "PDB entry 5sev coloured by chemically distinct molecules, front view.")
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>5sev</span> coloured by chemically distinct molecules, side view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>4 copies of <span class='highlight'>cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A</span>;</li> <li class='image_legend_li'>4 copies of <span class='highlight'>ZINC ION</span>;</li> <li class='image_legend_li'>4 copies of <span class='highlight'>MAGNESIUM ION</span>;</li> <li class='image_legend_li'>4 copies of <span class='highlight'>2,3,5-trimethyl-6-{2-[(4S)-1-methyl-4-phenyl-4,5-dihydro-1H-imidazol-2-yl]ethyl}pyrazine</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/5sev_deposited_chemically_distinct_molecules_side_image-800x800.png "PDB entry 5sev coloured by chemically distinct molecules, side view.")
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>5sev</span> coloured by chemically distinct molecules, top view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>4 copies of <span class='highlight'>cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A</span>;</li> <li class='image_legend_li'>4 copies of <span class='highlight'>ZINC ION</span>;</li> <li class='image_legend_li'>4 copies of <span class='highlight'>MAGNESIUM ION</span>;</li> <li class='image_legend_li'>4 copies of <span class='highlight'>2,3,5-trimethyl-6-{2-[(4S)-1-methyl-4-phenyl-4,5-dihydro-1H-imidazol-2-yl]ethyl}pyrazine</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/5sev_deposited_chemically_distinct_molecules_top_image-800x800.png "PDB entry 5sev coloured by chemically distinct molecules, top view.")
![<div class='caption-body'>Monomeric assembly 1 of PDB entry <span class='highlight'>5sev</span> contains 1 copy of <span class='highlight'>2,3,5-trimethyl-6-{2-[(4S)-1-methyl-4-phenyl-4,5-dihydro-1H-imidazol-2-yl]ethyl}pyrazine</span>. Front view.</div>](https://www.ebi.ac.uk/pdbe/static/entry/5sev_entity_4_front_image-800x800.png "2,3,5-trimethyl-6-{2-[(4S)-1-methyl-4-phenyl-4,5-dihydro-1H-imidazol-2-yl]ethyl}pyrazine in PDB entry 5sev, assembly 1, front view.")
![<div class='caption-body'>Monomeric assembly 1 of PDB entry <span class='highlight'>5sev</span> coloured by chemically distinct molecules, front view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>ZINC ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>MAGNESIUM ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>2,3,5-trimethyl-6-{2-[(4S)-1-methyl-4-phenyl-4,5-dihydro-1H-imidazol-2-yl]ethyl}pyrazine</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/5sev_assembly_1_chemically_distinct_molecules_front_image-800x800.png "Monomeric assembly 1 of PDB entry 5sev coloured by chemically distinct molecules, front view.")
![<div class='caption-body'>Monomeric assembly 1 of PDB entry <span class='highlight'>5sev</span> coloured by chemically distinct molecules, side view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>ZINC ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>MAGNESIUM ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>2,3,5-trimethyl-6-{2-[(4S)-1-methyl-4-phenyl-4,5-dihydro-1H-imidazol-2-yl]ethyl}pyrazine</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/5sev_assembly_1_chemically_distinct_molecules_side_image-800x800.png "Monomeric assembly 1 of PDB entry 5sev coloured by chemically distinct molecules, side view.")
![<div class='caption-body'>Monomeric assembly 1 of PDB entry <span class='highlight'>5sev</span> coloured by chemically distinct molecules, top view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>ZINC ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>MAGNESIUM ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>2,3,5-trimethyl-6-{2-[(4S)-1-methyl-4-phenyl-4,5-dihydro-1H-imidazol-2-yl]ethyl}pyrazine</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/5sev_assembly_1_chemically_distinct_molecules_top_image-800x800.png "Monomeric assembly 1 of PDB entry 5sev coloured by chemically distinct molecules, top view.")