› 5snb

X-ray diffraction
1.67Å resolution

PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant protein in complex with Z1545313172

Released:
DOI: 10.2210/pdb5snb/pdb
PDB entry 5snb coloured by chain, front view.
PDB entry 5snb coloured by chain, side view.
PDB entry 5snb coloured by chain, top view.
Source organism: Pseudomonas aeruginosa
Primary publication:
PanDDA analysis group deposition
Georgiou C, Espeland LO, Bukya H, Yadrykhinsky V, Haug BE, Mainkar P, Brenk R
Chemrxiv (2023)

Function and Biology Details

Reaction catalysed: 
A (Z)-hexadec-9-enoyl-[acyl-carrier protein] + a malonyl-[acyl-carrier protein] = a (Z)-3-oxooctadec-11-enoyl-[acyl-carrier protein] + CO(2) + an [acyl-carrier protein]
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-124418 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
3-oxoacyl-[acyl-carrier-protein] synthase 2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 414 amino acids
Theoretical weight: 43.57 KDa
Source organism: Pseudomonas aeruginosa
Expression system: Escherichia coli
UniProt:
  • Canonical: G3XDA2 (Residues: 1-414; Coverage: 100%)
Gene names: PA2965, fabF1
Sequence domains:

Ligands and Environments

3 bound ligands:
Ligand LWA 2 x LWA
Ligand DMS 8 x DMS
Ligand PO4 1 x PO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04-1
Spacegroup: C2
Unit cell:
a: 138.683Å b: 65.619Å c: 84.474Å
α: 90° β: 93.29° γ: 90°
R-values:
R R work R free
0.182 0.18 0.216
Expression system: Escherichia coli

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