Function and Biology

PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant protein in complex with Z30820160

Source organism: Pseudomonas aeruginosa
Biochemical function: metal ion binding
Biological process: fatty acid biosynthetic process
Cellular component: cytosol

EC 2.3.1.179: Beta-ketoacyl-[acyl-carrier-protein] synthase II

Reaction catalysed:
A (Z)-hexadec-9-enoyl-[acyl-carrier protein] + a malonyl-[acyl-carrier protein] = a (Z)-3-oxooctadec-11-enoyl-[acyl-carrier protein] + CO(2) + an [acyl-carrier protein]
Systematic name:
(Z)-hexadec-9-enoyl-[acyl-carrier protein]:malonyl-[acyl-carrier protein] C-acyltransferase (decarboxylating)
Alternative Name(s):
  • 3-oxoacyl-acyl carrier protein synthase I
  • Beta-ketoacyl-ACP synthase II
  • FabF
  • KAS II
  • KASII

Sequence families

Pfam Protein families (Pfam)
PF02801
Domain description: Beta-ketoacyl synthase, C-terminal domain
Occurring in:
  1. 3-oxoacyl-[acyl-carrier-protein] synthase 2
The deposited structure of PDB entry 5snt contains 2 copies of Pfam domain PF02801 (Beta-ketoacyl synthase, C-terminal domain) in 3-oxoacyl-[acyl-carrier-protein] synthase 2. Showing 1 copy in chain A.

PF00109
Domain description: Beta-ketoacyl synthase, N-terminal domain
Occurring in:
  1. 3-oxoacyl-[acyl-carrier-protein] synthase 2
The deposited structure of PDB entry 5snt contains 2 copies of Pfam domain PF00109 (Beta-ketoacyl synthase, N-terminal domain) in 3-oxoacyl-[acyl-carrier-protein] synthase 2. Showing 1 copy in chain A.