› 5t3p

X-ray diffraction
2.03Å resolution

Crystal structure of Human Peroxisomal coenzyme A diphosphatase NUDT7

Released:
DOI: 10.2210/pdb5t3p/pdb
PDB entry 5t3p coloured by chain, front view.
PDB entry 5t3p coloured by chain, side view.
PDB entry 5t3p coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Srikannathasan V, Nunez CA, Tallant C, Siejka P, Mathea S, Kopec J, Elkins JM, Burgess-Brown N, Arrowsmith CH, Edwards AM, Bountra C, von Delft F, Huber K

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-142851 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Peroxisomal coenzyme A diphosphatase NUDT7 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 236 amino acids
Theoretical weight: 26.71 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P0C024 (Residues: 1-235; Coverage: 99%)
Gene name: NUDT7
Sequence domains: NUDIX domain

Ligands and Environments

1 bound ligand:
Ligand EDO 10 x EDO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04-1
Spacegroup: P3121
Unit cell:
a: 113.73Å b: 113.73Å c: 108.2Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.18 0.177 0.225
Expression system: Escherichia coli BL21(DE3)

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