5t3s

X-ray diffraction
4.5Å resolution

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero octadecamer (preferred)
PDBe Complex ID:
PDB-CPX-231373 (preferred)
Entry contents:
6 distinct polypeptide molecules
Macromolecules (12 distinct):
Envelope glycoprotein gp160 Chain: G
Molecule details ›
Chain: G
Length: 481 amino acids
Theoretical weight: 54.15 KDa
Source organism: Human immunodeficiency virus 1
Expression system: Homo sapiens
UniProt:
  • Canonical: Q2N0S6 (Residues: 30-505; Coverage: 55%)
Gene name: env
Sequence domains: Envelope glycoprotein GP120
Transmembrane protein gp41 Chain: B
Molecule details ›
Chain: B
Length: 153 amino acids
Theoretical weight: 17.13 KDa
Source organism: Human immunodeficiency virus 1
Expression system: Homo sapiens
UniProt:
  • Canonical: Q2N0S6 (Residues: 509-661; Coverage: 18%)
Gene name: env
Sequence domains: Retroviral envelope protein
Fab PGT124 light chain Chain: L
Fab PGT124 heavy chain Chain: H
Fab 35022 heavy chain Chain: D
Fab 35022 light chain Chain: E

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
1 bound ligand:
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: APS BEAMLINE 23-ID-D
Spacegroup: P63
Unit cell:
a: 127.915Å b: 127.915Å c: 313.887Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.272 0.27 0.309
Expression system: Homo sapiens