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A Novel domain in human EXOG converts apoptotic endonuclease to DNA-repair enzyme

Source organisms:
Biochemical function: metal ion binding
Biological process: not assigned
Cellular component: not assigned

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GO terms

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence families

Pfam Protein families (Pfam)
PF18026
Domain description: Endo/exonuclease (EXOG) C-terminal domain
Occurring in:
  1. Nuclease EXOG, mitochondrial
The deposited structure of PDB entry 5t5c contains 2 copies of Pfam domain PF18026 (Endo/exonuclease (EXOG) C-terminal domain) in Nuclease EXOG, mitochondrial. Showing 1 copy in chain A.

PF01223
Domain description: DNA/RNA non-specific endonuclease
Occurring in:
  1. Nuclease EXOG, mitochondrial
The deposited structure of PDB entry 5t5c contains 2 copies of Pfam domain PF01223 (DNA/RNA non-specific endonuclease) in Nuclease EXOG, mitochondrial. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR001604
Domain description: DNA/RNA non-specific endonuclease/pyrophosphatase/phosphodiesterase domain
Occurring in:
  1. Nuclease EXOG, mitochondrial
IPR041003
Domain description: EXOG, C-terminal
Occurring in:
  1. Nuclease EXOG, mitochondrial
IPR020821
Domain description: ENPP1-3/EXOG-like, endonuclease/phosphodiesterase domain
Occurring in:
  1. Nuclease EXOG, mitochondrial
IPR044925
Domain description: His-Me finger superfamily
Occurring in:
  1. Nuclease EXOG, mitochondrial
IPR040255
Domain description: Non-specific endonuclease
Occurring in:
  1. Nuclease EXOG, mitochondrial
IPR044929
Domain description: DNA/RNA non-specific endonuclease superfamily
Occurring in:
  1. Nuclease EXOG, mitochondrial

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