5ttw

X-ray diffraction
1.74Å resolution

Crystal Structure of EED in Complex with UNC4859

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-522082 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Polycomb protein EED Chains: A, C
Molecule details ›
Chains: A, C
Length: 367 amino acids
Theoretical weight: 42.36 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O75530 (Residues: 76-441; Coverage: 83%)
Gene name: EED
Sequence domains: WD domain, G-beta repeat
Structure domains: YVTN repeat-like/Quinoprotein amine dehydrogenase
UNC4859 Chains: B, D
Molecule details ›
Chains: B, D
Length: 5 amino acids
Theoretical weight: 633 Da
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

2 bound ligands:
2 modified residues:

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-E
Spacegroup: C2
Unit cell:
a: 176.486Å b: 56.212Å c: 76.687Å
α: 90° β: 105.33° γ: 90°
R-values:
R R work R free
0.169 0.167 0.214
Expression systems:
  • Escherichia coli
  • Not provided