5txi

X-ray diffraction
1.6Å resolution

Crystal structure of wild-type S. aureus penicillin binding protein 4 (PBP4) in complex with ceftobiprole

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-173552 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Penicillin-binding protein 4, putative Chains: A, B
Molecule details ›
Chains: A, B
Length: 359 amino acids
Theoretical weight: 40.25 KDa
Source organism: Staphylococcus aureus
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q2G2X6 (Residues: 25-383; Coverage: 88%)
Gene name: SAOUHSC_00646
Sequence domains:
Structure domains:

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CLSI BEAMLINE 08ID-1
Spacegroup: C2
Unit cell:
a: 116.904Å b: 92.293Å c: 79.519Å
α: 90° β: 100.01° γ: 90°
R-values:
R R work R free
0.173 0.171 0.202
Expression system: Escherichia coli BL21