› 5ty6

X-ray diffraction
1.36Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-231434 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
VRC 315 13-1b02 Fab Heavy chain Chain: H
Molecule details ›
Chain: H
Length: 231 amino acids
Theoretical weight: 24.61 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Structure domains: Immunoglobulins
VRC 315 13-1b02 Fab Light chain Chain: L
Molecule details ›
Chain: L
Length: 212 amino acids
Theoretical weight: 23.18 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:
Ligand GOL 3 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P212121
Unit cell:
a: 64.942Å b: 79.055Å c: 107.723Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.16 0.159 0.173
Expression system: Homo sapiens

Quick links

Citations

17 review citations

Passive immunotherapy of viral infections: 'super-antibodies' enter the fray.
Walker et al. (2018)
16 more

1 mention without citation

Unique binding pattern for a lineage of human antibodies with broad reactivity against influenza A virus.
Sun et al. (2022)