› 5u8y

X-ray diffraction
2.5Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-566073 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Carotenoid cleavage oxygenase 1 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 526 amino acids
Theoretical weight: 59.5 KDa
Source organism: Neurospora crassa OR74A
Expression system: Escherichia coli
UniProt:
  • Canonical: Q7S860 (Residues: 1-526; Coverage: 100%)
Gene names: NCU07008, cao-1
Sequence domains: Retinal pigment epithelial membrane protein

Ligands and Environments

1 bound ligand:
Ligand CO 4 x CO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: P3221
Unit cell:
a: 100.44Å b: 100.44Å c: 447.977Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.187 0.185 0.223
Expression system: Escherichia coli

Quick links

Citations

5 review citations

The molecular aspects of absorption and metabolism of carotenoids and retinoids in vertebrates.
Widjaja-Adhi et al. (2020)
4 more

2 mentions without citation

Structure and Spectroscopy of Alkene-Cleaving Dioxygenases Containing an Atypically Coordinated Non-Heme Iron Center.
Sui et al. (2017)
1 more