5uby

X-ray diffraction
2.6Å resolution

Fab structure of anti-HIV-1 gp120 mAb 1A8

Released:
Source organism: Homo sapiens
Entry authors: Pan R, Kong X-P

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-231440 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Heavy chain of Fab fragment of anti-HIV1 gp120 mAb 1A8 Chain: H
Molecule details ›
Chain: H
Length: 228 amino acids
Theoretical weight: 24.29 KDa
Source organism: Homo sapiens
Expression system: Mammalia
Structure domains: Immunoglobulins
Light chain of Fab fragment of anti-HIV1 gp120 mAb 1A8 Chain: L
Molecule details ›
Chain: L
Length: 211 amino acids
Theoretical weight: 22.42 KDa
Source organism: Homo sapiens
Expression system: Mammalia
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL14-1
Spacegroup: C2
Unit cell:
a: 140.098Å b: 40.121Å c: 77.195Å
α: 90° β: 104.89° γ: 90°
R-values:
R R work R free
0.191 0.188 0.249
Expression system: Mammalia