5v8l

Electron Microscopy
4.3Å resolution

BG505 SOSIP.664 trimer in complex with broadly neutralizing HIV antibodies 3BNC117 and PGT145

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero tetradecamer (preferred)
PDBe Complex ID:
PDB-CPX-212135 (preferred)
Entry contents:
6 distinct polypeptide molecules
Macromolecules (13 distinct):
Envelope glycoprotein gp160 Chains: A, C, D
Molecule details ›
Chains: A, C, D
Length: 481 amino acids
Theoretical weight: 54.06 KDa
Source organism: Human immunodeficiency virus 1
Expression system: Homo sapiens
Transmembrane protein gp41 Chains: B, E, F
Molecule details ›
Chains: B, E, F
Length: 153 amino acids
Theoretical weight: 17.15 KDa
Source organism: Human immunodeficiency virus 1
Expression system: Homo sapiens
3BNC117 antibody, heavy chain Chains: G, H, I
PGT145 antibody, heavy chain Chain: J
3BNC117 antibody, light chain Chains: K, L, M
PGT145 antibody, light chain Chain: N

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer : NEW Components: NAG, BMA
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 4.3Å
Relevant EMDB volumes: EMD-8643
Expression system: Homo sapiens