EC 2.4.1.143: Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
Reaction catalysed:
UDP-N-acetyl-alpha-D-glucosamine + beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->6))-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-N-Asn-[protein] = UDP + beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-(beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6))-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-N-Asn-[protein]
Systematic name:
UDP-N-acetyl-alpha-D-glucosamine:alpha-D-mannosyl-(1->6)-beta-D-mannosyl-glycoprotein 2-beta-N-acetyl-D-glucosaminyltransferase (configuration-inverting)
Alternative Name(s):
- Acetylglucosaminyltransferase II
- Alpha-1,6-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
- GlcNAc-T II
- GnTII
- MGAT2 (gene name)
- N-acetylglucosaminyltransferase II
- N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase II
- UDP-GlcNAc:mannoside alpha-1-6 acetylglucosaminyltransferase
- UDP-N-acetyl-D-glucosamine:6-(alpha-D-mannosyl)-beta-D-mannosyl-glycoprotein 2-beta-N-acetyl-D-glucosaminyltransferase
- Uridine diphosphoacetylglucosamine-alpha-1,6-mannosylglycoprotein beta-1-2-N-acetylglucosaminyltransferase
- Uridine diphosphoacetylglucosamine-alpha-D-mannoside beta-1-2-acetylglucosaminyltransferase
- Uridine diphosphoacetylglucosamine-mannoside alpha-1->6-acetylglucosaminyltransferase
Protein family (Pfam)
InterPro annotations