5vku

Electron Microscopy
3.9Å resolution

An atomic structure of the human cytomegalovirus (HCMV) capsid with its securing layer of pp150 tegument protein

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero 3720-mer (preferred)
PDBe Complex ID:
PDB-CPX-140096 (preferred)
Entry contents:
5 distinct polypeptide molecules
Macromolecules (5 distinct):
Large structural phosphoprotein Chains: 0, 1, 2, 3, 4, 5, 6, 7, 8, 9, v, w, x, y, z
Molecule details ›
Chains: 0, 1, 2, 3, 4, 5, 6, 7, 8, 9, v, w, x, y, z
Length: 285 amino acids
Theoretical weight: 33.23 KDa
Source organism: Human herpesvirus 5 strain AD169
UniProt:
  • Canonical: P08318 (Residues: 1-285; Coverage: 27%)
Gene name: UL32
Major capsid protein Chains: A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P
Length: 1370 amino acids
Theoretical weight: 154.05 KDa
Source organism: Human herpesvirus 5 strain AD169
UniProt:
  • Canonical: P16729 (Residues: 1-1370; Coverage: 100%)
Gene names: MCP, UL86
Sequence domains: Herpes virus major capsid protein
Small capsomere-interacting protein Chains: Q, R, S, T, U, V, W, X, Y, Z, a, b, c, d, e, f
Triplex capsid protein 1 Chains: g, j, m, p, s
Triplex capsid protein 2 Chains: h, i, k, l, n, o, q, r, t, u

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.9Å
Relevant EMDB volumes: EMD-8703