5vot

Electron Microscopy
4.9Å resolution

Structure of AMPA receptor-TARP complex

Released:
Source organism: Rattus norvegicus
Related structures: EMD-8721

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero octamer (preferred)
PDBe Complex ID:
PDB-CPX-148613 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Glutamate receptor 2 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 889 amino acids
Theoretical weight: 99.53 KDa
Source organism: Rattus norvegicus
Expression system: Homo sapiens
UniProt:
  • Canonical: P19491 (Residues: 1-868, 869-883; Coverage: 100%)
  • Best match: P19491-3 (Residues: 1-848)
Gene names: GluA2, Glur2, Gria2
Sequence domains:
Voltage-dependent calcium channel gamma-2 subunit Chains: E, F, G, H
Molecule details ›
Chains: E, F, G, H
Length: 323 amino acids
Theoretical weight: 35.94 KDa
Source organism: Rattus norvegicus
Expression system: Homo sapiens
UniProt:
  • Canonical: Q71RJ2 (Residues: 1-323; Coverage: 100%)
Gene names: Cacng2, Stg
Sequence domains: PMP-22/EMP/MP20/Claudin family

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 4.9Å
Relevant EMDB volumes: EMD-8721
Expression system: Homo sapiens