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Crystal structure of EBV gHgL/CL40/gp42 N-domain

Source organisms:
Biochemical function: protein binding
Biological process: symbiont entry into host cell
Cellular component: virion membrane

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GO terms

Sequence families

Pfam Protein families (Pfam)
PF11108
Domain description: Viral glycoprotein L
Occurring in:
  1. Envelope glycoprotein L
The deposited structure of PDB entry 5w0k contains 2 copies of Pfam domain PF11108 (Viral glycoprotein L) in Envelope glycoprotein L. Showing 1 copy in chain B.

PF17488
Domain description: Herpesvirus glycoprotein H C-terminal domain
Occurring in:
  1. Envelope glycoprotein H
The deposited structure of PDB entry 5w0k contains 2 copies of Pfam domain PF17488 (Herpesvirus glycoprotein H C-terminal domain) in Envelope glycoprotein H. Showing 1 copy in chain A.

PF02489
Domain description: Herpesvirus glycoprotein H main domain
Occurring in:
  1. Envelope glycoprotein H
The deposited structure of PDB entry 5w0k contains 2 copies of Pfam domain PF02489 (Herpesvirus glycoprotein H main domain) in Envelope glycoprotein H. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR003597
Domain description: Immunoglobulin C1-set
Occurring in:
  1. CL40 IgG heavy chain
  2. CL40 IgG light chain
IPR013106
Domain description: Immunoglobulin V-set domain
Occurring in:
  1. CL40 IgG heavy chain
  2. CL40 IgG light chain
IPR036179
Domain description: Immunoglobulin-like domain superfamily
Occurring in:
  1. CL40 IgG heavy chain
  2. CL40 IgG light chain
IPR013783
Domain description: Immunoglobulin-like fold
Occurring in:
  1. CL40 IgG heavy chain
  2. CL40 IgG light chain
IPR007110
Domain description: Immunoglobulin-like domain
Occurring in:
  1. CL40 IgG heavy chain
  2. CL40 IgG light chain
IPR003599
Domain description: Immunoglobulin domain subtype
Occurring in:
  1. CL40 IgG heavy chain
  2. CL40 IgG light chain
IPR003006
Domain description: Immunoglobulin/major histocompatibility complex, conserved site
Occurring in:
  1. CL40 IgG light chain
IPR020175
Domain description: Herpesvirus glycoprotein L, rhadinovirus-type
Occurring in:
  1. Envelope glycoprotein L
IPR038313
Domain description: Herpesvirus glycoprotein L, rhadinovirus-type superfamily
Occurring in:
  1. Envelope glycoprotein L
IPR034708
Domain description: Envelope glycoprotein L
Occurring in:
  1. Envelope glycoprotein L
IPR038172
Domain description: Herpesvirus glycoprotein H, C-terminal domain superfamily
Occurring in:
  1. Envelope glycoprotein H
IPR035305
Domain description: Herpesvirus glycoprotein H, C-terminal
Occurring in:
  1. Envelope glycoprotein H
IPR003493
Domain description: Herpesvirus glycoprotein H
Occurring in:
  1. Envelope glycoprotein H

Structure domains

CATH CATH domains
2.60.40.10
Class: Mainly Beta
Architecture: Sandwich
Topology: Immunoglobulin-like
Homology: Immunoglobulins
Occurring in:
  1. CL40 IgG heavy chain
  2. CL40 IgG light chain
The deposited structure of PDB entry 5w0k contains 2 copies of CATH domain 2.60.40.10 (Immunoglobulin-like) in CL40 IgG heavy chain. Showing 1 copy in chain H [auth E].
The deposited structure of PDB entry 5w0k contains 4 copies of CATH domain 2.60.40.10 (Immunoglobulin-like) in CL40 IgG light chain. Showing 2 copies in chain I [auth F].
3.10.390.20
Class: Alpha Beta
Architecture: Roll
Topology: SAND domain
Homology: Viral glycoprotein L
Occurring in:
  1. Envelope glycoprotein L
The deposited structure of PDB entry 5w0k contains 2 copies of CATH domain 3.10.390.20 (SAND domain) in Envelope glycoprotein L. Showing 1 copy in chain B.
3.90.380.20
Class: Alpha Beta
Architecture: Alpha-Beta Complex
Topology: Naphthalene 1,2-dioxygenase Alpha Subunit; Chain A, domain 1
Homology: Herpesvirus glycoprotein H, domain D-II
Occurring in:
  1. Envelope glycoprotein H
The deposited structure of PDB entry 5w0k contains 2 copies of CATH domain 3.90.380.20 (Naphthalene 1,2-dioxygenase Alpha Subunit; Chain A, domain 1) in Envelope glycoprotein H. Showing 1 copy in chain A.

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