Function and Biology Details
Reactions catalysed:
A beta-D-glucuronoside + H(2)O = D-glucuronate + an alcohol
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Biochemical function:
Biological process:
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-145804 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Klotho
Molecule details ›
Chain: A
Length: 981 amino acids
Theoretical weight: 112.67 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains: Glycosyl hydrolase family 1
Length: 981 amino acids
Theoretical weight: 112.67 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical:
Q9UEF7 (Residues: 1-981; Coverage: 97%)
Sequence domains: Glycosyl hydrolase family 1
Fibroblast growth factor 23 N-terminal peptide
Molecule details ›
Chain: B
Length: 226 amino acids
Theoretical weight: 25.41 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Fibroblast growth factor
Length: 226 amino acids
Theoretical weight: 25.41 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: Q9GZV9 (Residues: 25-204; Coverage: 79%)
Sequence domains: Fibroblast growth factor
Fibroblast growth factor receptor 1
Molecule details ›
Chain: C
Length: 226 amino acids
Theoretical weight: 25.38 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Immunoglobulin I-set domain
Structure domains: Immunoglobulins
Length: 226 amino acids
Theoretical weight: 25.38 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: P11362 (Residues: 142-365; Coverage: 28%)
Sequence domains: Immunoglobulin I-set domain
Structure domains: Immunoglobulins
