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5wbr Overview
![<div class='caption-body'>Homo dimeric assembly 1 of PDB entry <span class='highlight'>5wbr</span> coloured by chemically distinct molecules, front view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>2 copies of <span class='highlight'>Ketohexokinase</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-[(3S)-3-(hydroxymethyl)piperidin-1-yl]-4-(trifluoromethyl)pyridine-3-carbonitrile</span>;</li> <li class='image_legend_li'>5 copies of <span class='highlight'>SULFATE ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>CITRIC ACID</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>GLYCEROL</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/5wbr_assembly_1_chemically_distinct_molecules_front_image-800x800.png "Homo dimeric assembly 1 of PDB entry 5wbr coloured by chemically distinct molecules, front view.")
![<div class='caption-body'>Homo dimeric assembly 1 of PDB entry <span class='highlight'>5wbr</span> coloured by chemically distinct molecules, side view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>2 copies of <span class='highlight'>Ketohexokinase</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-[(3S)-3-(hydroxymethyl)piperidin-1-yl]-4-(trifluoromethyl)pyridine-3-carbonitrile</span>;</li> <li class='image_legend_li'>5 copies of <span class='highlight'>SULFATE ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>CITRIC ACID</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>GLYCEROL</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/5wbr_assembly_1_chemically_distinct_molecules_side_image-800x800.png "Homo dimeric assembly 1 of PDB entry 5wbr coloured by chemically distinct molecules, side view.")
![<div class='caption-body'>Homo dimeric assembly 1 of PDB entry <span class='highlight'>5wbr</span> coloured by chemically distinct molecules, top view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>2 copies of <span class='highlight'>Ketohexokinase</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-[(3S)-3-(hydroxymethyl)piperidin-1-yl]-4-(trifluoromethyl)pyridine-3-carbonitrile</span>;</li> <li class='image_legend_li'>5 copies of <span class='highlight'>SULFATE ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>CITRIC ACID</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>GLYCEROL</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/5wbr_assembly_1_chemically_distinct_molecules_top_image-800x800.png "Homo dimeric assembly 1 of PDB entry 5wbr coloured by chemically distinct molecules, top view.")
![<div class='caption-body'>Homo dimeric assembly 1 of PDB entry <span class='highlight'>5wbr</span> coloured by chain, front view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>2 copies of <span class='highlight'>Ketohexokinase</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-[(3S)-3-(hydroxymethyl)piperidin-1-yl]-4-(trifluoromethyl)pyridine-3-carbonitrile</span>;</li> <li class='image_legend_li'>5 copies of <span class='highlight'>SULFATE ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>CITRIC ACID</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>GLYCEROL</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/5wbr_assembly_1_chain_front_image-800x800.png "Homo dimeric assembly 1 of PDB entry 5wbr coloured by chain, front view.")
![<div class='caption-body'>Homo dimeric assembly 1 of PDB entry <span class='highlight'>5wbr</span> coloured by chain, side view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>2 copies of <span class='highlight'>Ketohexokinase</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-[(3S)-3-(hydroxymethyl)piperidin-1-yl]-4-(trifluoromethyl)pyridine-3-carbonitrile</span>;</li> <li class='image_legend_li'>5 copies of <span class='highlight'>SULFATE ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>CITRIC ACID</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>GLYCEROL</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/5wbr_assembly_1_chain_side_image-800x800.png "Homo dimeric assembly 1 of PDB entry 5wbr coloured by chain, side view.")
![<div class='caption-body'>Homo dimeric assembly 1 of PDB entry <span class='highlight'>5wbr</span> coloured by chain, top view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>2 copies of <span class='highlight'>Ketohexokinase</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-[(3S)-3-(hydroxymethyl)piperidin-1-yl]-4-(trifluoromethyl)pyridine-3-carbonitrile</span>;</li> <li class='image_legend_li'>5 copies of <span class='highlight'>SULFATE ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>CITRIC ACID</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>GLYCEROL</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/5wbr_assembly_1_chain_top_image-800x800.png "Homo dimeric assembly 1 of PDB entry 5wbr coloured by chain, top view.")
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>5wbr</span> coloured by chain, front view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>2 copies of <span class='highlight'>Ketohexokinase</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-[(3S)-3-(hydroxymethyl)piperidin-1-yl]-4-(trifluoromethyl)pyridine-3-carbonitrile</span>;</li> <li class='image_legend_li'>5 copies of <span class='highlight'>SULFATE ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>CITRIC ACID</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>GLYCEROL</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/5wbr_deposited_chain_front_image-800x800.png "PDB entry 5wbr coloured by chain, front view.")
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>5wbr</span> coloured by chain, side view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>2 copies of <span class='highlight'>Ketohexokinase</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-[(3S)-3-(hydroxymethyl)piperidin-1-yl]-4-(trifluoromethyl)pyridine-3-carbonitrile</span>;</li> <li class='image_legend_li'>5 copies of <span class='highlight'>SULFATE ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>CITRIC ACID</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>GLYCEROL</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/5wbr_deposited_chain_side_image-800x800.png "PDB entry 5wbr coloured by chain, side view.")
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>5wbr</span> coloured by chain, top view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>2 copies of <span class='highlight'>Ketohexokinase</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-[(3S)-3-(hydroxymethyl)piperidin-1-yl]-4-(trifluoromethyl)pyridine-3-carbonitrile</span>;</li> <li class='image_legend_li'>5 copies of <span class='highlight'>SULFATE ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>CITRIC ACID</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>GLYCEROL</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/5wbr_deposited_chain_top_image-800x800.png "PDB entry 5wbr coloured by chain, top view.")
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>5wbr</span> coloured by chemically distinct molecules, front view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>2 copies of <span class='highlight'>Ketohexokinase</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-[(3S)-3-(hydroxymethyl)piperidin-1-yl]-4-(trifluoromethyl)pyridine-3-carbonitrile</span>;</li> <li class='image_legend_li'>5 copies of <span class='highlight'>SULFATE ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>CITRIC ACID</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>GLYCEROL</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/5wbr_deposited_chemically_distinct_molecules_front_image-800x800.png "PDB entry 5wbr coloured by chemically distinct molecules, front view.")
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>5wbr</span> coloured by chemically distinct molecules, side view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>2 copies of <span class='highlight'>Ketohexokinase</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-[(3S)-3-(hydroxymethyl)piperidin-1-yl]-4-(trifluoromethyl)pyridine-3-carbonitrile</span>;</li> <li class='image_legend_li'>5 copies of <span class='highlight'>SULFATE ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>CITRIC ACID</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>GLYCEROL</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/5wbr_deposited_chemically_distinct_molecules_side_image-800x800.png "PDB entry 5wbr coloured by chemically distinct molecules, side view.")
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>5wbr</span> coloured by chemically distinct molecules, top view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>2 copies of <span class='highlight'>Ketohexokinase</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-[(3S)-3-(hydroxymethyl)piperidin-1-yl]-4-(trifluoromethyl)pyridine-3-carbonitrile</span>;</li> <li class='image_legend_li'>5 copies of <span class='highlight'>SULFATE ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>CITRIC ACID</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>GLYCEROL</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/5wbr_deposited_chemically_distinct_molecules_top_image-800x800.png "PDB entry 5wbr coloured by chemically distinct molecules, top view.")