› 5wcc

X-ray diffraction
2.46Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-231465 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
VRC 315 02-1F07 Fab Heavy chain Chains: A, H
Molecule details ›
Chains: A, H
Length: 227 amino acids
Theoretical weight: 24.28 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Structure domains: Immunoglobulins
VRC 315 02-1F07 Fab Light chain Chains: B, L
Molecule details ›
Chains: B, L
Length: 217 amino acids
Theoretical weight: 23.19 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Structure domains: Immunoglobulins

Ligands and Environments

3 bound ligands:
Ligand SO4 5 x SO4
Ligand 15P 3 x 15P
Ligand GOL 1 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: C2
Unit cell:
a: 179.217Å b: 70.581Å c: 94.543Å
α: 90° β: 111.86° γ: 90°
R-values:
R R work R free
0.205 0.203 0.24
Expression system: Homo sapiens

Quick links

Citations

17 review citations

Passive immunotherapy of viral infections: 'super-antibodies' enter the fray.
Walker et al. (2018)
16 more

1 mention without citation

Selection and Modelling of a New Single-Domain Intrabody Against TDP-43.
Gilodi et al. (2021)