› 5x29

Solution NMR

NMR structure of the SARS Coronavirus E protein pentameric ion channel

Released:
DOI: 10.2210/pdb5x29/pdb
PDB entry 5x29 coloured by chain, ensemble of 16 models, front view.
PDB entry 5x29 coloured by chain, ensemble of 16 models, side view.
PDB entry 5x29 coloured by chain, ensemble of 16 models, top view.
Source organism: Severe acute respiratory syndrome-related coronavirus
Primary publication:
Structural model of the SARS coronavirus E channel in LMPG micelles.
Surya W, Li Y, Torres J
OpenAccess logo Biochim Biophys Acta Biomembr 1860 1309-1317 (2018)
PMID: 29474890

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo pentamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-157833 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Envelope small membrane protein Chains: A, B, C, D, E
Molecule details ›
Chains: A, B, C, D, E
Length: 81 amino acids
Theoretical weight: 9 KDa
Source organism: Severe acute respiratory syndrome-related coronavirus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P59637 (Residues: 8-65; Coverage: 76%)
Gene names: 4, E, sM
Sequence domains: Coronavirus small envelope protein E

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 19%
Refinement method: simulated annealing
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

17 review citations

Structural Proteins in Severe Acute Respiratory Syndrome Coronavirus-2.
Satarker et al. (2020)
16 more

69 mentions without citation

COVID-19 Outbreak: An Overview.
Ciotti et al. (2019)
68 more