› 5x9u

X-ray diffraction
4Å resolution

Crystal structure of group III chaperonin in the open state

Released:
DOI: 10.2210/pdb5x9u/pdb
PDB entry 5x9u coloured by chain, front view.
PDB entry 5x9u coloured by chain, side view.
PDB entry 5x9u coloured by chain, top view.
Source organism: Carboxydothermus hydrogenoformans Z-2901
Primary publication:
Structural and mechanistic characterization of an archaeal-like chaperonin from a thermophilic bacterium.
An YJ, Rowland SE, Na JH, Spigolon D, Hong SK, Yoon YJ, Lee JH, Robb FT, Cha SS
OpenAccess logo Nat Commun 8 827 (2017)
PMID: 29018216

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo hexadecamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-174510 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Thermosome, alpha subunit Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 521 amino acids
Theoretical weight: 56.69 KDa
Source organism: Carboxydothermus hydrogenoformans Z-2901
Expression system: Escherichia coli
UniProt:
  • Canonical: Q3AF10 (Residues: 1-521; Coverage: 100%)
Gene name: CHY_0413
Sequence domains: TCP-1/cpn60 chaperonin family
Structure domains: GroEL-like equatorial domain

Ligands and Environments

1 bound ligand:
Ligand ADP 4 x ADP
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE BL-1A
Spacegroup: P4212
Unit cell:
a: 209.78Å b: 209.78Å c: 169.813Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.256 0.253 0.321
Expression system: Escherichia coli

Quick links

Citations

3 review citations

Complex Destabilization in the Mitochondrial Chaperonin Hsp60 Leads to Disease.
Rodriguez et al. (2020)
2 more

3 mentions without citation

A Glimpse Into the Structure and Function of Atypical Type I Chaperonins.
Ansari et al. (2018)
2 more