EC 5.3.3.12: L-dopachrome isomerase
Reaction catalysed:
L-dopachrome = 5,6-dihydroxyindole-2-carboxylate
Systematic name:
L-dopachrome keto-enol isomerase
Alternative Name(s):
- DCF
- DCT
- Dopachrome Delta(7),Delta(2)-isomerase
- Dopachrome Delta-isomerase
- Dopachrome conversion factor
- Dopachrome isomerase
- Dopachrome keto-enol isomerase
- Dopachrome oxidoreductase
- Dopachrome rearranging enzyme
- Dopachrome tautomerase
- Dopachrome-rearranging enzyme
- L-dopachrome-methyl ester tautomerase
- TRP
- TRP-1
- TRP-2
- TRP2
- Tryosinase-related protein-2
- Tyrosinase-related protein 2
EC 5.3.2.1: Phenylpyruvate tautomerase
Reaction catalysed:
Keto-phenylpyruvate = enol-phenylpyruvate
Systematic name:
Phenylpyruvate keto--enol-isomerase
Alternative Name(s):
- Phenylpyruvate keto--enol tautomerase
- Phenylpyruvic keto--enol isomerase
GO terms
Biochemical function:
Biological process:
- negative regulation of cellular senescence
- positive regulation of chemokine (C-X-C motif) ligand 2 production
- negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
- positive regulation of cAMP/PKA signal transduction
- cellular senescence
- positive regulation of arachidonate secretion
- positive regulation of ERK1 and ERK2 cascade
- protein homotrimerization
- positive regulation of myeloid leukocyte cytokine production involved in immune response
- positive regulation of prostaglandin secretion involved in immune response
- negative regulation of protein metabolic process
- positive chemotaxis
- positive regulation of fibroblast proliferation
- innate immune response
- negative regulation of DNA damage response, signal transduction by p53 class mediator
- negative regulation of apoptotic process
- regulation of macrophage activation
- positive regulation of phosphorylation
- regulation of cell population proliferation
- negative regulation of myeloid cell apoptotic process
- positive regulation of tumor necrosis factor production
- positive regulation of lipopolysaccharide-mediated signaling pathway
- positive regulation of B cell proliferation
- negative regulation of cell migration
- DNA damage response, signal transduction by p53 class mediator
- carboxylic acid metabolic process
- negative regulation of macrophage chemotaxis
- negative regulation of gene expression
- positive regulation of cell population proliferation
- cell surface receptor signaling pathway
- inflammatory response
- negative regulation of mature B cell apoptotic process
- positive regulation of cytokine production
- prostaglandin biosynthetic process
Protein family (Pfam)
InterPro annotations
CATH domain