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Crystal structure of human Smad2-Ski complex

Source organism: Homo sapiens
Biochemical function: not assigned
Biological process: regulation of DNA-templated transcription
Cellular component: not assigned

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GO terms

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF03166
Domain description: MH2 domain
Occurring in:
  1. Mothers against decapentaplegic homolog 2
The deposited structure of PDB entry 5xod contains 1 copy of Pfam domain PF03166 (MH2 domain) in Mothers against decapentaplegic homolog 2. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR001132
Domain description: SMAD domain, Dwarfin-type
Occurring in:
  1. Mothers against decapentaplegic homolog 2
IPR017855
Domain description: SMAD-like domain superfamily
Occurring in:
  1. Mothers against decapentaplegic homolog 2
IPR013790
Domain description: Dwarfin
Occurring in:
  1. Mothers against decapentaplegic homolog 2
IPR008984
Domain description: SMAD/FHA domain superfamily
Occurring in:
  1. Mothers against decapentaplegic homolog 2

Structure domain

CATH CATH domain
2.60.200.10
Class: Mainly Beta
Architecture: Sandwich
Topology: Tumour Suppressor Smad4
Homology: Tumour Suppressor Smad4
Occurring in:
  1. Mothers against decapentaplegic homolog 2
The deposited structure of PDB entry 5xod contains 1 copy of CATH domain 2.60.200.10 (Tumour Suppressor Smad4) in Mothers against decapentaplegic homolog 2. Showing 1 copy in chain A.

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