EC 2.8.1.7: Cysteine desulfurase
Reaction catalysed:
(1a) L-cysteine + [enzyme]-cysteine = L-alanine + [enzyme]-S-sulfanylcysteine
Systematic name:
L-cysteine:acceptor sulfurtransferase
Alternative Name(s):
- Cysteine desulfurylase
- IscS
- NIFS
- NifS
- SufS
GO terms
Biochemical function:
Biological process:
Cellular component:
Sequence families
Protein families (Pfam)
![The deposited structure of PDB entry 5xt6 contains 1 copy of Pfam domain PF01592 (NifU-like N terminal domain) in Zinc-dependent sulfurtransferase SufU. Showing 1 copy in chain A [auth D].](https://www.ebi.ac.uk/pdbe/static/entry/5xt6_1_D_Pfam_PF01592_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>5xt6</span> contains 1 copy of Pfam domain <span class='highlight'>PF01592 (NifU-like N terminal domain)</span> in <span class='highlight'>Zinc-dependent sulfurtransferase SufU</span>. Showing 1 copy in chain <span class='highlight'>A [auth D]</span>.")
![The deposited structure of PDB entry 5xt6 contains 1 copy of Pfam domain PF01592 (NifU-like N terminal domain) in Zinc-dependent sulfurtransferase SufU. Showing 1 copy in chain D [auth C].](https://www.ebi.ac.uk/pdbe/static/entry/5xt6_3_C_Pfam_PF01592_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>5xt6</span> contains 1 copy of Pfam domain <span class='highlight'>PF01592 (NifU-like N terminal domain)</span> in <span class='highlight'>Zinc-dependent sulfurtransferase SufU</span>. Showing 1 copy in chain <span class='highlight'>D [auth C]</span>.")
![The deposited structure of PDB entry 5xt6 contains 2 copies of Pfam domain PF00266 (Aminotransferase class-V) in Cysteine desulfurase SufS. Showing 1 copy in chain B [auth A].](https://www.ebi.ac.uk/pdbe/static/entry/5xt6_2_A_Pfam_PF00266_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>5xt6</span> contains 2 copies of Pfam domain <span class='highlight'>PF00266 (Aminotransferase class-V)</span> in <span class='highlight'>Cysteine desulfurase SufS</span>. Showing 1 copy in chain <span class='highlight'>B [auth A]</span>.")
InterPro annotations
IPR020578
Domain description:
Aminotransferase class-V, pyridoxal-phosphate binding site
Occurring in:
Occurring in:
CATH domain![The deposited structure of PDB entry 5xt6 contains 1 copy of CATH domain 3.90.1010.10 (Sufe protein. Chain: A) in Zinc-dependent sulfurtransferase SufU. Showing 1 copy in chain A [auth D].](https://www.ebi.ac.uk/pdbe/static/entry/5xt6_1_D_CATH_3.90.1010.10_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>5xt6</span> contains 1 copy of CATH domain <span class='highlight'>3.90.1010.10 (Sufe protein. Chain: A)</span> in <span class='highlight'>Zinc-dependent sulfurtransferase SufU</span>. Showing 1 copy in chain <span class='highlight'>A [auth D]</span>.")
![The deposited structure of PDB entry 5xt6 contains 1 copy of CATH domain 3.90.1010.10 (Sufe protein. Chain: A) in Zinc-dependent sulfurtransferase SufU. Showing 1 copy in chain D [auth C].](https://www.ebi.ac.uk/pdbe/static/entry/5xt6_3_C_CATH_3.90.1010.10_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>5xt6</span> contains 1 copy of CATH domain <span class='highlight'>3.90.1010.10 (Sufe protein. Chain: A)</span> in <span class='highlight'>Zinc-dependent sulfurtransferase SufU</span>. Showing 1 copy in chain <span class='highlight'>D [auth C]</span>.")