› 5xws

X-ray diffraction
3.08Å resolution

Crystal structure of SALM5 LRR-Ig

Released:
DOI: 10.2210/pdb5xws/pdb
PDB entry 5xws coloured by chain, front view.
PDB entry 5xws coloured by chain, side view.
PDB entry 5xws coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structural basis of trans-synaptic interactions between PTPδ and SALMs for inducing synapse formation.
Goto-Ito S, Yamagata A, Sato Y, Uemura T, Shiroshima T, Maeda A, Imai A, Mori H, Yoshida T, Fukai S
OpenAccess logo Nat Commun 9 269 (2018)
PMID: 29348429

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-188647 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Leucine-rich repeat and fibronectin type-III domain-containing protein 5 Chain: A
Molecule details ›
Chain: A
Length: 367 amino acids
Theoretical weight: 41.38 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q96NI6 (Residues: 18-379; Coverage: 52%)
Gene names: C14orf146, LRFN5, SALM5
Sequence domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE BL-1A
Spacegroup: P6322
Unit cell:
a: 154.888Å b: 154.888Å c: 91.262Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.27 0.268 0.308
Expression system: Homo sapiens

Quick links

Citations

4 review citations

SALM/Lrfn Family Synaptic Adhesion Molecules.
Lie et al. (2018)
3 more

1 mention without citation

Structural basis of trans-synaptic interactions between PTPδ and SALMs for inducing synapse formation.
Goto-Ito et al. (2018)