› 5y4t

X-ray diffraction
1.4Å resolution

Crystal structure of Trx domain of Grx3 from Saccharomyces cerevisiae

Released:
DOI: 10.2210/pdb5y4t/pdb
PDB entry 5y4t coloured by chain, front view.
PDB entry 5y4t coloured by chain, side view.
PDB entry 5y4t coloured by chain, top view.
Source organism: Saccharomyces cerevisiae YJM789
Primary publication:
Structural and Biochemical Insights into the Multiple Functions of Yeast Grx3.
Chi CB, Tang Y, Zhang J, Dai YN, Abdalla M, Chen Y, Zhou CZ
J Mol Biol 430 1235-1248 (2018)
PMID: 29524511

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-108192 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Thioredoxin domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 122 amino acids
Theoretical weight: 13.77 KDa
Source organism: Saccharomyces cerevisiae YJM789
Expression system: Escherichia coli
UniProt:
  • Canonical: A6ZY62 (Residues: 36-149; Coverage: 40%)
Gene names: GRX3, SCY_1000
Sequence domains: Thioredoxin
Structure domains: Glutaredoxin

Ligands and Environments

1 bound ligand:
Ligand GOL 2 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U1
Spacegroup: P41212
Unit cell:
a: 77.329Å b: 77.329Å c: 37.113Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.19 0.189 0.219
Expression system: Escherichia coli

Quick links

Citations

1 review citation

Iron-sulfur cluster biogenesis, trafficking, and signaling: Roles for CGFS glutaredoxins and BolA proteins.
Talib et al. (2021)
6 other articles

1 mention without citation

Comparison of structures among Saccharomyces cerevisiae Grxs proteins.
Abdalla et al. (2018)