› 5yh7

X-ray diffraction
2.03Å resolution

Crystal structure of the complex of Phosphopantetheine adenylyltransferase from Acinetobacter baumannii with Coenzyme A at 2.0 A resolution

Released:
DOI: 10.2210/pdb5yh7/pdb
PDB entry 5yh7 coloured by chain, front view.
PDB entry 5yh7 coloured by chain, side view.
PDB entry 5yh7 coloured by chain, top view.
Source organism: Acinetobacter baumannii ACICU
Primary publication:
Structural and binding studies of phosphopantetheine adenylyl transferase from Acinetobacter baumannii.
Gupta A, Singh PK, Iqbal N, Sharma P, Baraigya HR, Kaur P, Umar MS, Ahmad F, Sharma A, Owais M, Sharma S, Singh TP
Biochim Biophys Acta Proteins Proteom 1867 537-547 (2019)
PMID: 30885618

Function and Biology Details

Reaction catalysed: 
ATP + pantetheine 4'-phosphate = diphosphate + 3'-dephospho-CoA
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-109605 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Phosphopantetheine adenylyltransferase Chain: A
Molecule details ›
Chain: A
Length: 163 amino acids
Theoretical weight: 18.48 KDa
Source organism: Acinetobacter baumannii ACICU
Expression system: Escherichia coli
UniProt:
  • Canonical: B2HUN5 (Residues: 1-163; Coverage: 100%)
Gene names: ACICU_00798, coaD
Sequence domains: Cytidylyltransferase-like
Structure domains: HUPs

Ligands and Environments

2 bound ligands:
Ligand COA 1 x COA
Ligand SO4 3 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: F4132
Unit cell:
a: 216.93Å b: 216.93Å c: 216.93Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.199 0.198 0.215
Expression system: Escherichia coli

Quick links