› 5z4u

X-ray diffraction
3.18Å resolution

Crystal Structure of T2R-TTL complex with 7a3

Released:
DOI: 10.2210/pdb5z4u/pdb
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PDB entry 5z4u coloured by chain, front view.
PDB entry 5z4u coloured by chain, side view.
PDB entry 5z4u coloured by chain, top view.
Source organisms:
Entry authors: Lai Q, Wang Y, Yang J, Yao Y

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
PDBe Complex ID:
PDB-CPX-237205 (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (4 distinct):
Tubulin alpha-1B chain Chains: A, C
Molecule details ›
Chains: A, C
Length: 450 amino acids
Theoretical weight: 50.04 KDa
Source organism: Sus scrofa
Expression system: Escherichia coli
UniProt:
  • Canonical: Q2XVP4 (Residues: 1-450; Coverage: 100%)
Gene name: TUBA1B
Sequence domains:
Structure domains:
Tubulin beta-2B chain Chains: B, D
Molecule details ›
Chains: B, D
Length: 445 amino acids
Theoretical weight: 49.94 KDa
Source organism: Bos taurus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q6B856 (Residues: 1-445; Coverage: 100%)
Gene name: TUBB2B
Sequence domains:
Structure domains:
Stathmin-4 Chain: E
Tubulin tyrosine ligase Chain: F

Ligands and Environments

7 bound ligands:
Ligand GTP 3 x GTP
Ligand MG 4 x MG
Ligand CA 3 x CA
Ligand GDP 1 x GDP
Ligand MES 2 x MES
Ligand 96C 2 x 96C
Ligand ACP 1 x ACP
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: SSRF BEAMLINE BL19U1
Spacegroup: P212121
Unit cell:
a: 105.491Å b: 158.233Å c: 182.099Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.19 0.188 0.235
Expression system: Escherichia coli

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