› 5zvf

Solution NMR

Structure of [T9,K7]indolicidin, a non glycosylated analogue of indolicidin

Released:
DOI: 10.2210/pdb5zvf/pdb
PDB entry 5zvf coloured by chain, ensemble of 20 models, front view.
PDB entry 5zvf coloured by chain, ensemble of 20 models, side view.
PDB entry 5zvf coloured by chain, ensemble of 20 models, top view.
Source organism: Bos taurus
Primary publication:
Design of therapeutically improved analogue of the antimicrobial peptide, indolicidin, using a glycosylation strategy.
Dwivedi R, Aggarwal P, Bhavesh NS, Kaur KJ
Amino Acids 51 1443-1460 (2019)
PMID: 31485742

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-152537 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cathelicidin-4 Chain: A
Molecule details ›
Chain: A
Length: 14 amino acids
Theoretical weight: 1.86 KDa
Source organism: Bos taurus
Expression system: Not provided
UniProt:
  • Canonical: P33046 (Residues: 131-143; Coverage: 11%)
Gene name: CATHL4

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 36%
Refinement method: simulated annealing
Expression system: Not provided

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Citations

2 review citations

Indolicidin revisited: biological activity, potential applications and perspectives of an antimicrobial peptide not yet fully explored.
Batista Araujo et al. (2022)
1 more