› 5zyx

Solution NMR

Solution NMR structure of K30 peptide in 10 mM dioctanoyl phosphatidylglycerol (D8PG)

Released:
DOI: 10.2210/pdb5zyx/pdb
PDB entry 5zyx coloured by chain, ensemble of 20 models, front view.
PDB entry 5zyx coloured by chain, ensemble of 20 models, side view.
PDB entry 5zyx coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Design, Synthesis, Antibacterial Potential, and Structural Characterization of N-Acylated Derivatives of the Human Autophagy 16 Polypeptide.
Varnava KG, Mohid SA, Calligari P, Stella L, Reynison J, Bhunia A, Sarojini V
Bioconjug Chem 30 1998-2010 (2019)
PMID: 31145591

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-179295 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Autophagy-related protein 16-1 Chain: A
Molecule details ›
Chain: A
Length: 20 amino acids
Theoretical weight: 2.7 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q676U5 (Residues: 12-31; Coverage: 3%)
Gene names: APG16L, ATG16L1, UNQ9393/PRO34307

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 38%
Refinement method: simulated annealing
Expression system: Not provided

Quick links

Citations

2 review citations

Lipidation of Antimicrobial Peptides as a Design Strategy for Future Alternatives to Antibiotics.
Rounds et al. (2020)
1 more