6cbj

X-ray diffraction
2.85Å resolution

Crystal Structure of DH270.3 Fab in complex with Man9

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-180183 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (3 distinct):
Ig-like domain-containing protein Chain: H
Molecule details ›
Chain: H
Length: 238 amino acids
Theoretical weight: 25.8 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: S6C4S0 (Residues: 20-119, 120-247; Coverage: 88%)
Sequence domains:
Structure domains: Immunoglobulins
Ig-like domain-containing protein Chain: L
Molecule details ›
Chain: L
Length: 216 amino acids
Theoretical weight: 22.75 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q6PJG0 (Residues: 20-235; Coverage: 100%)
Sequence domains:
Structure domains: Immunoglobulins

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA, MAN
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-E
Spacegroup: I41
Unit cell:
a: 128.087Å b: 128.087Å c: 91.875Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.205 0.204 0.231
Expression system: Homo sapiens