› 6du9

X-ray diffraction
2.33Å resolution

Crystal Structure of Human Prion Protein 90-231

Released:
DOI: 10.2210/pdb6du9/pdb
PDB entry 6du9 coloured by chain, front view.
PDB entry 6du9 coloured by chain, side view.
PDB entry 6du9 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Nonato MC, Rangel VL, Pavlovici FA

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo tetramer
Assembly name:
PDBe Complex ID:
PDB-CPX-137455 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Major prion protein Chain: A
Molecule details ›
Chain: A
Length: 141 amino acids
Theoretical weight: 16.08 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P04156 (Residues: 90-230; Coverage: 61%)
Gene names: ALTPRP, PRIP, PRNP, PRP
Sequence domains: Prion/Doppel alpha-helical domain

Ligands and Environments

2 bound ligands:
Ligand CD 3 x CD
Ligand CL 1 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04-1
Spacegroup: I4122
Unit cell:
a: 72.17Å b: 72.17Å c: 158.55Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.197 0.192 0.235
Expression system: Escherichia coli BL21(DE3)

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