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6et4 Overview
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![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>6et4</span> coloured by chain, front view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>Dihydroorotate dehydrogenase (quinone), mitochondrial</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>FLAVIN MONONUCLEOTIDE</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>(4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>N-[(4R)-1-(2-fluorophenyl)-4,5,6,7-tetrahydroindazol-4-yl]-2,1-benzoxazole-3-carboxamide</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>DECYLAMINE-N,N-DIMETHYL-N-OXIDE</span>;</li> <li class='image_legend_li'>4 copies of <span class='highlight'>ACETIC ACID</span>;</li> <li class='image_legend_li'>3 copies of <span class='highlight'>GLYCEROL</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>SULFATE ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>CHLORIDE ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/6et4_deposited_chain_front_image-800x800.png "PDB entry 6et4 coloured by chain, front view.")
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>6et4</span> coloured by chain, side view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>Dihydroorotate dehydrogenase (quinone), mitochondrial</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>FLAVIN MONONUCLEOTIDE</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>(4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>N-[(4R)-1-(2-fluorophenyl)-4,5,6,7-tetrahydroindazol-4-yl]-2,1-benzoxazole-3-carboxamide</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>DECYLAMINE-N,N-DIMETHYL-N-OXIDE</span>;</li> <li class='image_legend_li'>4 copies of <span class='highlight'>ACETIC ACID</span>;</li> <li class='image_legend_li'>3 copies of <span class='highlight'>GLYCEROL</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>SULFATE ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>CHLORIDE ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/6et4_deposited_chain_side_image-800x800.png "PDB entry 6et4 coloured by chain, side view.")
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>6et4</span> coloured by chain, top view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>Dihydroorotate dehydrogenase (quinone), mitochondrial</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>FLAVIN MONONUCLEOTIDE</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>(4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>N-[(4R)-1-(2-fluorophenyl)-4,5,6,7-tetrahydroindazol-4-yl]-2,1-benzoxazole-3-carboxamide</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>DECYLAMINE-N,N-DIMETHYL-N-OXIDE</span>;</li> <li class='image_legend_li'>4 copies of <span class='highlight'>ACETIC ACID</span>;</li> <li class='image_legend_li'>3 copies of <span class='highlight'>GLYCEROL</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>SULFATE ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>CHLORIDE ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/6et4_deposited_chain_top_image-800x800.png "PDB entry 6et4 coloured by chain, top view.")
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>6et4</span> coloured by chemically distinct molecules, front view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>Dihydroorotate dehydrogenase (quinone), mitochondrial</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>FLAVIN MONONUCLEOTIDE</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>(4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>N-[(4R)-1-(2-fluorophenyl)-4,5,6,7-tetrahydroindazol-4-yl]-2,1-benzoxazole-3-carboxamide</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>DECYLAMINE-N,N-DIMETHYL-N-OXIDE</span>;</li> <li class='image_legend_li'>4 copies of <span class='highlight'>ACETIC ACID</span>;</li> <li class='image_legend_li'>3 copies of <span class='highlight'>GLYCEROL</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>SULFATE ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>CHLORIDE ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/6et4_deposited_chemically_distinct_molecules_front_image-800x800.png "PDB entry 6et4 coloured by chemically distinct molecules, front view.")
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>6et4</span> coloured by chemically distinct molecules, side view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>Dihydroorotate dehydrogenase (quinone), mitochondrial</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>FLAVIN MONONUCLEOTIDE</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>(4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>N-[(4R)-1-(2-fluorophenyl)-4,5,6,7-tetrahydroindazol-4-yl]-2,1-benzoxazole-3-carboxamide</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>DECYLAMINE-N,N-DIMETHYL-N-OXIDE</span>;</li> <li class='image_legend_li'>4 copies of <span class='highlight'>ACETIC ACID</span>;</li> <li class='image_legend_li'>3 copies of <span class='highlight'>GLYCEROL</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>SULFATE ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>CHLORIDE ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/6et4_deposited_chemically_distinct_molecules_side_image-800x800.png "PDB entry 6et4 coloured by chemically distinct molecules, side view.")
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>6et4</span> coloured by chemically distinct molecules, top view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>Dihydroorotate dehydrogenase (quinone), mitochondrial</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>FLAVIN MONONUCLEOTIDE</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>(4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>N-[(4R)-1-(2-fluorophenyl)-4,5,6,7-tetrahydroindazol-4-yl]-2,1-benzoxazole-3-carboxamide</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>DECYLAMINE-N,N-DIMETHYL-N-OXIDE</span>;</li> <li class='image_legend_li'>4 copies of <span class='highlight'>ACETIC ACID</span>;</li> <li class='image_legend_li'>3 copies of <span class='highlight'>GLYCEROL</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>SULFATE ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>CHLORIDE ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/6et4_deposited_chemically_distinct_molecules_top_image-800x800.png "PDB entry 6et4 coloured by chemically distinct molecules, top view.")
![<div class='caption-body'>Monomeric assembly 1 of PDB entry <span class='highlight'>6et4</span> contains 1 copy of <span class='highlight'>N-[(4R)-1-(2-fluorophenyl)-4,5,6,7-tetrahydroindazol-4-yl]-2,1-benzoxazole-3-carboxamide</span>. Front view.</div>](https://www.ebi.ac.uk/pdbe/static/entry/6et4_entity_4_front_image-800x800.png "N-[(4R)-1-(2-fluorophenyl)-4,5,6,7-tetrahydroindazol-4-yl]-2,1-benzoxazole-3-carboxamide in PDB entry 6et4, assembly 1, front view.")
![<div class='caption-body'>Monomeric assembly 1 of PDB entry <span class='highlight'>6et4</span> coloured by chemically distinct molecules, front view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>Dihydroorotate dehydrogenase (quinone), mitochondrial</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>FLAVIN MONONUCLEOTIDE</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>(4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>N-[(4R)-1-(2-fluorophenyl)-4,5,6,7-tetrahydroindazol-4-yl]-2,1-benzoxazole-3-carboxamide</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>DECYLAMINE-N,N-DIMETHYL-N-OXIDE</span>;</li> <li class='image_legend_li'>4 copies of <span class='highlight'>ACETIC ACID</span>;</li> <li class='image_legend_li'>3 copies of <span class='highlight'>GLYCEROL</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>SULFATE ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>CHLORIDE ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/6et4_assembly_1_chemically_distinct_molecules_front_image-800x800.png "Monomeric assembly 1 of PDB entry 6et4 coloured by chemically distinct molecules, front view.")
![<div class='caption-body'>Monomeric assembly 1 of PDB entry <span class='highlight'>6et4</span> coloured by chemically distinct molecules, side view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>Dihydroorotate dehydrogenase (quinone), mitochondrial</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>FLAVIN MONONUCLEOTIDE</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>(4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>N-[(4R)-1-(2-fluorophenyl)-4,5,6,7-tetrahydroindazol-4-yl]-2,1-benzoxazole-3-carboxamide</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>DECYLAMINE-N,N-DIMETHYL-N-OXIDE</span>;</li> <li class='image_legend_li'>4 copies of <span class='highlight'>ACETIC ACID</span>;</li> <li class='image_legend_li'>3 copies of <span class='highlight'>GLYCEROL</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>SULFATE ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>CHLORIDE ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/6et4_assembly_1_chemically_distinct_molecules_side_image-800x800.png "Monomeric assembly 1 of PDB entry 6et4 coloured by chemically distinct molecules, side view.")
![<div class='caption-body'>Monomeric assembly 1 of PDB entry <span class='highlight'>6et4</span> coloured by chemically distinct molecules, top view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>Dihydroorotate dehydrogenase (quinone), mitochondrial</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>FLAVIN MONONUCLEOTIDE</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>(4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>N-[(4R)-1-(2-fluorophenyl)-4,5,6,7-tetrahydroindazol-4-yl]-2,1-benzoxazole-3-carboxamide</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>DECYLAMINE-N,N-DIMETHYL-N-OXIDE</span>;</li> <li class='image_legend_li'>4 copies of <span class='highlight'>ACETIC ACID</span>;</li> <li class='image_legend_li'>3 copies of <span class='highlight'>GLYCEROL</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>SULFATE ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>CHLORIDE ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/6et4_assembly_1_chemically_distinct_molecules_top_image-800x800.png "Monomeric assembly 1 of PDB entry 6et4 coloured by chemically distinct molecules, top view.")