› 6fjo

X-ray diffraction
1.17Å resolution

Adenovirus species 26 knob protein, very high resolution

Released:
DOI: 10.2210/pdb6fjo/pdb
PDB entry 6fjo coloured by chain, front view.
PDB entry 6fjo coloured by chain, side view.
PDB entry 6fjo coloured by chain, top view.
Source organism: Human adenovirus 26
Primary publication:
Human adenovirus type 26 uses sialic acid-bearing glycans as a primary cell entry receptor.
Baker AT, Mundy RM, Davies JA, Rizkallah PJ, Parker AL
OpenAccess logo Sci Adv 5 eaax3567 (2019)
PMID: 31517055

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-107523 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Adenoviral fibre protein knob domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 183 amino acids
Theoretical weight: 20.65 KDa
Source organism: Human adenovirus 26
Expression system: Escherichia coli
UniProt:
  • Canonical: A4ZKM1 (Residues: 186-368; Coverage: 49%)
Sequence domains: Adenoviral fibre protein (knob domain)
Structure domains: Adenovirus pIV-related, attachment domain

Ligands and Environments

3 bound ligands:
Ligand GLU 1 x GLU
Ligand SO4 1 x SO4
Ligand GOL 1 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: P213
Unit cell:
a: 85.776Å b: 85.776Å c: 85.776Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.17 0.169 0.19
Expression system: Escherichia coli

Quick links

Citations

18 review citations

Factors Which Contribute to the Immunogenicity of Non-replicating Adenoviral Vectored Vaccines.
Coughlan L. (2020)
17 more

1 mention without citation

Human adenovirus type 26 uses sialic acid-bearing glycans as a primary cell entry receptor.
Baker et al. (2019)