› 6fxs

X-ray diffraction
2.01Å resolution

Structure of Trypanosoma brucei type B ribose 5-phosphate isomerase

Released:
DOI: 10.2210/pdb6fxs/pdb
Model geometry
Fit model/data
PDB entry 6fxs coloured by chain, front view.
PDB entry 6fxs coloured by chain, side view.
PDB entry 6fxs coloured by chain, top view.
Source organism: Trypanosoma brucei brucei TREU927
Entry authors: Ronin C, Ciesielski F, Ciapetti P

Function and Biology Details

Reaction catalysed: 
D-ribose 5-phosphate = D-ribulose 5-phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-174334 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Ribose 5-phosphate isomerase, putative Chain: A
Molecule details ›
Chain: A
Length: 175 amino acids
Theoretical weight: 19.18 KDa
Source organism: Trypanosoma brucei brucei TREU927
Expression system: Escherichia coli
UniProt:
  • Canonical: Q384D1 (Residues: 1-155; Coverage: 100%)
Gene name: Tb11.01.0700
Sequence domains: Ribose/Galactose Isomerase
Structure domains: Sugar-phosphate isomerase, RpiB/LacA/LacB
Ribose 5-phosphate isomerase, putative Chain: B
Molecule details ›
Chain: B
Length: 175 amino acids
Theoretical weight: 19.15 KDa
Source organism: Trypanosoma brucei brucei TREU927
Expression system: Escherichia coli
UniProt:
  • Canonical: Q384D1 (Residues: 1-155; Coverage: 100%)
Gene name: Tb11.01.0700
Sequence domains: Ribose/Galactose Isomerase
Structure domains: Sugar-phosphate isomerase, RpiB/LacA/LacB

Ligands and Environments

1 bound ligand:
Ligand SO4 3 x SO4
1 modified residue:
Ligand CSD 1 x CSD

Experiments and Validation Details

Entry percentile scores
X-ray source: SOLEIL BEAMLINE PROXIMA 1
Spacegroup: P4122
Unit cell:
a: 97.8Å b: 97.8Å c: 84.18Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.166 0.164 0.198
Expression system: Escherichia coli

Quick links

PDB-REDO

The sliders below show the change in model quality between original PDB entry and the PDB-REDO entry

Model Geometry
 
 
Data not available
DNA/RNA Geometry
 
 
Data not available
Fit model/data
 
 
Data not available
PDB-REDO