› 6mlw

X-ray diffraction
1.9Å resolution

Crystal structure of X. citri phosphoglucomutase in complex with 2-fluoro mannosyl-1-methyl-phosphonic acid

Released:
DOI: 10.2210/pdb6mlw/pdb
PDB entry 6mlw coloured by chain, front view.
PDB entry 6mlw coloured by chain, side view.
PDB entry 6mlw coloured by chain, top view.
Source organism: Xanthomonas citri
Primary publication:
Inhibitory Evaluation of αPMM/PGM from Pseudomonas aeruginosa: Chemical Synthesis, Enzyme Kinetics, and Protein Crystallographic Study.
Zhu JS, Stiers KM, Soleimani E, Groves BR, Beamer LJ, Jakeman DL
J Org Chem 84 9627-9636 (2019)
PMID: 31264865

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-241489 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Phosphoglucomutase Chain: A
Molecule details ›
Chain: A
Length: 468 amino acids
Theoretical weight: 51.22 KDa
Source organism: Xanthomonas citri
Expression system: Escherichia coli

Ligands and Environments

2 bound ligands:
Ligand MG 1 x MG
Ligand JVA 1 x JVA
1 modified residue:
Ligand SEP 1 x SEP

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 4.2.2
Spacegroup: P212121
Unit cell:
a: 43.781Å b: 54.587Å c: 172.909Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.192 0.189 0.249
Expression system: Escherichia coli

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Citations

5 citation in other articles

Handling Several Sugars at a Time: a Case Study of Xyloglucan Utilization by Ruminiclostridium cellulolyticum.
Kampik et al. (2021)
4 more