6odd

X-ray diffraction
2Å resolution

Crystal structure of the human complex ACP-ISD11

Released:
Source organism: Homo sapiens
Primary publication:
Structure of the Human ACP-ISD11 Heterodimer.
Biochemistry 58 4596-4609 (2019)
PMID: 31664822

Function and Biology Details

Structure analysis Details

Assemblies composition:
hetero tetramer
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-127010 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Acyl carrier protein, mitochondrial Chain: A
Molecule details ›
Chain: A
Length: 85 amino acids
Theoretical weight: 9.85 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O14561 (Residues: 72-156; Coverage: 55%)
Gene name: NDUFAB1
Sequence domains: Phosphopantetheine attachment site
LYR motif-containing protein 4 Chain: B
Molecule details ›
Chain: B
Length: 74 amino acids
Theoretical weight: 8.83 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9HD34 (Residues: 5-78; Coverage: 81%)
Gene names: C6orf149, CGI-203, ISD11, LYRM4
Sequence domains: Complex 1 protein (LYR family)

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SOLEIL BEAMLINE PROXIMA 2
Spacegroup: I213
Unit cell:
a: 123.19Å b: 123.19Å c: 123.19Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.194 0.192 0.216
Expression system: Escherichia coli