› 6pb3

X-ray diffraction
2.05Å resolution

Structure of Rhizobiales Trip13

Released:
DOI: 10.2210/pdb6pb3/pdb
PDB entry 6pb3 coloured by chain, front view.
PDB entry 6pb3 coloured by chain, side view.
PDB entry 6pb3 coloured by chain, top view.
Source organism: marine metagenome
Primary publication:
HORMA Domain Proteins and a Trip13-like ATPase Regulate Bacterial cGAS-like Enzymes to Mediate Bacteriophage Immunity.
Ye Q, Lau RK, Mathews IT, Birkholz EA, Watrous JD, Azimi CS, Pogliano J, Jain M, Corbett KD
Mol Cell 77 709-722.e7 (2020)
PMID: 31932165

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-495459 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
AAA+ ATPase domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 312 amino acids
Theoretical weight: 33.71 KDa
Source organism: marine metagenome
Expression system: Escherichia coli
UniProt:
  • Canonical: A0A1B3NHK7 (Residues: 1-312; Coverage: 100%)
Gene name: BSY19_1118
Sequence domains: ATPase family associated with various cellular activities (AAA)

Ligands and Environments

1 bound ligand:
Ligand SO4 1 x SO4
1 modified residue:
Ligand MSE 7 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-E
Spacegroup: P6
Unit cell:
a: 100.436Å b: 100.436Å c: 48.86Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.211 0.208 0.252
Expression system: Escherichia coli

Quick links

Citations

24 review citations

Bacterial origins of human cell-autonomous innate immune mechanisms.
Wein et al. (2022)
23 more

1 mention without citation

HORMA Domain Proteins and a Trip13-like ATPase Regulate Bacterial cGAS-like Enzymes to Mediate Bacteriophage Immunity.
Ye et al. (2020)